OBJECTIVE: This study aimed to identify diagnostic biomarkers for keloid and explore potential therapeutic agents from traditional Chinese medicine (TCM) by integrating network pharmacology approaches. Specifically, we sought to uncover key molecular...
BACKGROUND: Intervertebral disc degeneration (IDD) is prevalent in orthopaedics, yet lacks effective treatments. This study seeks to discover potential therapeutic targets for IDD to inform clinical therapies and traditional medicine approaches.
Named Entity Recognition (NER) plays a crucial role in extracting important information such as treatment methods, symptoms, and herbal prescriptions from Traditional Chinese Medicine (TCM) electronic medical records. However, existing NER methods of...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Oct 30, 2025
BACKGROUND: Target identification is fundamental to drug discovery, facilitating mechanistic elucidation and therapeutic target identification. Traditional herbal medicines exert therapeutic effects through multi-component, multi-target synergistic m...
Journal of pharmaceutical and biomedical analysis
Oct 22, 2025
Sinapis Semen, as a traditional Chinese medicine, has an unclear relationship between its stir-frying degrees and sensory characteristics. Therefore, it is essential to develop a multi-index evaluation method to classify the processing degree of Sina...
This study integrated ancient Traditional Chinese Medicine (TCM) pulse diagnosis techniques with modern machine learning to advance contemporary medical diagnostics. A portable intelligent TCM pulse diagnostic device was developed using MEMS and CMOS...
BACKGROUND: Traditional Chinese medicine (TCM) education in China has evolved significantly, shaped by both national policy and social needs. Despite this, the academic community has yet to fully explore the long-term trends and core issues in TCM ed...
RESEARCH PURPOSE: This study proposes MMFi-DPBML, a deep learning framework that in-tegrates multi-molecular fingerprint features for predicting ingredient-target interactions (ITIs) in traditional Chinese medicine (TCM). By capturing di-verse struct...
BACKGROUND: Several clinical cases and experiments have demonstrated the effectiveness of traditional Chinese medicine (TCM) formulas in treating and preventing diseases. These formulas contain critical information about their ingredients, efficacy, ...
BACKGROUND: Syndrome differentiation in traditional Chinese medicine (TCM) is an ancient principle that guides disease diagnosis and treatment. Among these, the cold and hot syndromes play a crucial role in identifying the nature of the disease and g...
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