International journal of medical informatics
36577203
BACKGROUND: Cognitive tests and biomarkers are the key information to assess the severity and track the progression of Alzheimer's' disease (AD) and AD-related dementias (AD/ADRD), yet, both are often only documented in clinical narratives of patient...
IMPORTANCE: Until now, other than complex neurologic tests, there have been no readily accessible and reliable indicators of neurologic dysfunction among patients with Parkinson disease (PD). This study was conducted to determine the role of fundus p...
Advances in experimental medicine and biology
39400832
BACKGROUND: Recently, a method using deep learning has been developed to estimate the risk of developing dementia. This method uses general blood test data from routine health examinations that reveal lifestyle-related diseases, which can lead to vas...
BACKGROUND: Primary outcome measure in the clinical trials of disease modifying therapy (DMT) drugs for Alzheimer's disease (AD) has often been evaluated by Clinical Dementia Rating sum of boxes (CDRSB). However, CDR testing requires specialized trai...
This study aimed to address the issue of larger prediction errors existing in intelligent predictive tasks related to Alzheimer's disease (AD). A cohort of 487 enrolled participants was categorized into three groups: normal control (138 individuals),...
BACKGROUND AND OBJECTIVE: Early identification of post-stroke cognitive impairment (PSCI) is an important challenge for clinicians. In this study, we aimed to build a machine learning-based prediction model for PSCI and uncover potential risk factors...
OBJECTIVE: Dementia is a significant medical and social issue in most developed countries. Practical tools for predicting the progression of degenerative dementia are highly valuable. Machine learning (ML) methods facilitate the construction of effec...
Journal of the American Medical Informatics Association : JAMIA
39520712
OBJECTIVE: This study aims to automate the prediction of Mini-Mental State Examination (MMSE) scores, a widely adopted standard for cognitive assessment in patients with Alzheimer's disease, using natural language processing (NLP) and machine learnin...
BACKGROUND: Dementia is a multifaceted disorder that affects cognitive function, necessitating accurate diagnosis for effective management and treatment. Although the Mini-Mental State Examination (MMSE) is widely used to assess cognitive impairment,...