AIMC Topic: Methylation

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Identifying RNA 5-methylcytosine sites via pseudo nucleotide compositions.

Molecular bioSystems Oct 18, 2016
RNA 5-methylcytosine (mC) plays an important role in numerous biological processes. Accurate identification of the mC site is helpful for a better understanding of its biological functions. However, the drawbacks of the experimental methods available...
Humans Algorithms Reproducibility of Results Computational Biology Epigenomics Support Vector Machine RNA Methylation Nucleic Acid Conformation 5-Methylcytosine
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LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns.

Oncotarget Nov 24, 2015
Accumulating evidences suggest that long non-coding RNAs (lncRNAs) perform important functions. Genome-wide chromatin-states area rich source of information about cellular state, yielding insights beyond what is typically obtained by transcriptome pr...
Humans Algorithms Cells, Cultured Neoplasms Gene Expression Profiling Cell Line, Tumor Gene Regulatory Networks RNA, Messenger Models, Genetic Hep G2 Cells Cell Line RNA, Long Noncoding HeLa Cells Methylation Promoter Regions, Genetic Lysine K562 Cells Histones Gene Ontology Chromatin Transcription Initiation Site
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