AIMC Topic: Microinjections

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Development of a Microforce Sensor and Its Array Platform for Robotic Cell Microinjection Force Measurement.

Sensors (Basel, Switzerland) Apr 6, 2016
Robot-assisted cell microinjection, which is precise and can enable a high throughput, is attracting interest from researchers. Conventional probe-type cell microforce sensors have some real-time injection force measurement limitations, which prevent...
Microinjections Cell Transplantation Robotics Stress, Mechanical Zebrafish Mice Cell Line Biosensing Techniques Animals
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Computer-Assisted Transgenesis of Caenorhabditis elegans for Deep Phenotyping.

Genetics Jul 10, 2015
A major goal in the study of human diseases is to assign functions to genes or genetic variants. The model organism Caenorhabditis elegans provides a powerful tool because homologs of many human genes are identifiable, and large collections of geneti...
Algorithms Humans Phenotype Gene Transfer Techniques Automation, Laboratory Robotics Animals Microinjections Caenorhabditis elegans Animals, Genetically Modified
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Robotic adherent cell injection for characterizing cell-cell communication.

IEEE transactions on bio-medical engineering Jul 24, 2014
Compared to robotic injection of suspended cells (e.g., embryos and oocytes), fewer attempts were made to automate the injection of adherent cells (e.g., cancer cells and cardiomyocytes) due to their smaller size, highly irregular morphology, small t...
Micromanipulation Microinjections Cell Adhesion Robotics Cell Separation Mice Cell Communication Man-Machine Systems Equipment Design Myocytes, Cardiac Cell Line Cell Transplantation Animals Equipment Failure Analysis
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High-throughput genetic manipulation of multicellular organisms using a machine-vision guided embryonic microinjection robot.

Genetics Apr 3, 2024
Microinjection is a technique used for transgenesis, mutagenesis, cell labeling, cryopreservation, and in vitro fertilization in multiple single and multicellular organisms. Microinjection requires specialized skills and involves rate-limiting and la...
Animals Robotics Humans Drosophila melanogaster Microinjections Animals, Genetically Modified Zebrafish
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Multiscale, multi-perspective imaging assisted robotic microinjection of 3D biological structures.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Nov 1, 2021
Microinjection is a widely used technique employed by biologists with applications in transgenesis, cryopreservation, mutagenesis, labeling/dye injection and in-vitro fertilization. However, microinjection is an extremely laborious manual procedure, ...
Zebrafish Microinjections Drosophila melanogaster Robotics Robotic Surgical Procedures Animals
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Assessing the Role of Teleoperated Robotic Systems in Biomanipulations - A Case Study on Blastocyst Microinjection.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Jul 1, 2018
Blastocyst microinjections, like many other biomanipulation tasks, involve delicate and precise manual control of micropipettes under a microscope. The operations are carried out by highly trained operators who spend hours peering through the binocul...
Robotics Microscopy Microinjections Blastocyst
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