AIMC Topic: Mitosis

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Machine learning techniques for mitoses classification.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
BACKGROUND: Pathologists analyze biopsy material at both the cellular and structural level to determine diagnosis and cancer stage. Mitotic figures are surrogate biomarkers of cellular proliferation that can provide prognostic information; thus, thei...

Prediction of Sequential Organelles Localization under Imbalance using A Balanced Deep U-Net.

Scientific reports
Assessing the structure and function of organelles in living organisms of the primitive unicellular red algae Cyanidioschyzon merolae on three-dimensional sequential images demands a reliable automated technique in the class imbalance among various c...

Sequential Saliency Guided Deep Neural Network for Joint Mitosis Identification and Localization in Time-Lapse Phase Contrast Microscopy Images.

IEEE journal of biomedical and health informatics
The analysis of cell mitotic behavior plays important role in many biomedical research and medical diagnostic applications. To improve the accuracy of mitosis detection in automated analysis systems, this paper proposes the sequential saliency guided...

Cell mitosis event analysis in phase contrast microscopy images using deep learning.

Medical image analysis
In this paper, we solve the problem of mitosis event localization and its stage localization in time-lapse phase-contrast microscopy images. Our method contains three steps: first, we formulate a Low-Rank Matrix Recovery (LRMR) model to find salient ...

Detecting mitotic cells in HEp-2 images as anomalies via one class classifier.

Computers in biology and medicine
We propose a novel framework for classification of mitotic v/s non-mitotic cells in a Computer Aided Diagnosis (CAD) system for Anti-Nuclear Antibodies (ANA) detection. In the proposed work, due to unique characteristics (the rare occurrence) of the ...

Deep learning and manual assessment show that the absolute mitotic count does not contain prognostic information in triple negative breast cancer.

Cellular oncology (Dordrecht, Netherlands)
PURPOSE: The prognostic value of mitotic count for invasive breast cancer is firmly established. As yet, however, limited studies have been aimed at assessing mitotic counts as a prognostic factor for triple negative breast cancers (TNBC). Here, we a...

Training Convolutional Neural Networks and Compressed Sensing End-to-End for Microscopy Cell Detection.

IEEE transactions on medical imaging
Automated cell detection and localization from microscopy images are significant tasks in biomedical research and clinical practice. In this paper, we design a new cell detection and localization algorithm that combines deep convolutional neural netw...

Predicting breast tumor proliferation from whole-slide images: The TUPAC16 challenge.

Medical image analysis
Tumor proliferation is an important biomarker indicative of the prognosis of breast cancer patients. Assessment of tumor proliferation in a clinical setting is a highly subjective and labor-intensive task. Previous efforts to automate tumor prolifera...

Efficient automated detection of mitotic cells from breast histological images using deep convolution neutral network with wavelet decomposed patches.

Computers in biology and medicine
In medical practice, the mitotic cell count from histological images acts as a proliferative marker for cancer diagnosis. Therefore, an accurate method for detecting mitotic cells in histological images is essential for cancer screening. Manual evalu...

DeepMitosis: Mitosis detection via deep detection, verification and segmentation networks.

Medical image analysis
Mitotic count is a critical predictor of tumor aggressiveness in the breast cancer diagnosis. Nowadays mitosis counting is mainly performed by pathologists manually, which is extremely arduous and time-consuming. In this paper, we propose an accurate...