Tumor proliferation is an important biomarker indicative of the prognosis of breast cancer patients. Assessment of tumor proliferation in a clinical setting is a highly subjective and labor-intensive task. Previous efforts to automate tumor prolifera...
Automated cell detection and localization from microscopy images are significant tasks in biomedical research and clinical practice. In this paper, we design a new cell detection and localization algorithm that combines deep convolutional neural netw...
PURPOSE: The prognostic value of mitotic count for invasive breast cancer is firmly established. As yet, however, limited studies have been aimed at assessing mitotic counts as a prognostic factor for triple negative breast cancers (TNBC). Here, we a...
We propose a novel framework for classification of mitotic v/s non-mitotic cells in a Computer Aided Diagnosis (CAD) system for Anti-Nuclear Antibodies (ANA) detection. In the proposed work, due to unique characteristics (the rare occurrence) of the ...
In this paper, we solve the problem of mitosis event localization and its stage localization in time-lapse phase-contrast microscopy images. Our method contains three steps: first, we formulate a Low-Rank Matrix Recovery (LRMR) model to find salient ...
IEEE journal of biomedical and health informatics
31545751
The analysis of cell mitotic behavior plays important role in many biomedical research and medical diagnostic applications. To improve the accuracy of mitosis detection in automated analysis systems, this paper proposes the sequential saliency guided...
Assessing the structure and function of organelles in living organisms of the primitive unicellular red algae Cyanidioschyzon merolae on three-dimensional sequential images demands a reliable automated technique in the class imbalance among various c...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
33302246
BACKGROUND: Pathologists analyze biopsy material at both the cellular and structural level to determine diagnosis and cancer stage. Mitotic figures are surrogate biomarkers of cellular proliferation that can provide prognostic information; thus, thei...
IEEE journal of biomedical and health informatics
32991296
Mitotic count is an important indicator for assessing the invasiveness of breast cancers. Currently, the number of mitoses is manually counted by pathologists, which is both tedious and time-consuming. To address this situation, we propose a fast and...
IEEE/ACM transactions on computational biology and bioinformatics
31144644
Mitosis detection is one of the challenging steps in biomedical imaging research, which can be used to observe the cell behavior. Most of the already existing methods that are applied in detecting mitosis usually contain many nonmitotic events (norma...