High-dimensional linear classifiers, such as distance weighted discrimination (DWD) and versions of the support vector machine (SVM), are commonly used in biomedical research to distinguish groups of subjects based on a large number of features. Howe...
Advances in experimental medicine and biology
Jan 1, 2017
Motor impairments are very common in multiple sclerosis (MS), leading to a reduced Quality of Life and active participation. In the past decades, new insights into the functional reorganization processes that occur after a brain injury have been intr...
Journal of managed care & specialty pharmacy
Dec 1, 2016
BACKGROUND: Multiple sclerosis (MS), a central nervous system disease in which nerve signals are disrupted by scarring and demyelination, is classified into phenotypes depending on the patterns of cognitive or physical impairment progression: relapsi...
IEEE journal of biomedical and health informatics
Sep 1, 2015
Quantitative measurements from segmentations of human brain magnetic resonance (MR) images provide important biomarkers for normal aging and disease progression. In this paper, we propose a patch-based tissue classification method from MR images that...
Technology and health care : official journal of the European Society for Engineering and Medicine
Jan 1, 2015
BACKGROUND: Medical image segmentation is an essential step for most consequent image analysis tasks. Medical images can be segmented manually, but the accuracy of image segmentation using the automated segmentation algorithms is more when compared w...
International journal of data mining and bioinformatics
Jan 1, 2015
Early classification of time series has been receiving a lot of attention recently. In this paper we present a model, which we call the Early Classification Model (ECM), that allows for early, accurate and patient-specific classification of multivari...
Studies in health technology and informatics
Jan 1, 2015
People suffering from neuromuscular disorders are one of the main target groups of speech-controlled Ambient Assisted Living systems. However, the speech of these patients is often distorted because of the dysarthric symptoms of the disease. The dysa...