AIMC Topic: Narcolepsy

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Development and validation of a machine learning model for prediction of comorbid major depression disorder among narcolepsy type 1.

Sleep medicine
BACKGROUND: Major depression disorder (MDD) forms a common psychiatric comorbidity among patients with narcolepsy type 1 (NT1), yet its impact on patients with NT1 is often overlooked by neurologists. Currently, there is a lack of effective methods f...

Identifying time-resolved features of nocturnal sleep characteristics of narcolepsy using machine learning.

Journal of sleep research
The differential diagnosis of narcolepsy type 1, a rare, chronic, central disorder of hypersomnolence, is challenging due to overlapping symptoms with other hypersomnolence disorders. While recent years have seen significant growth in our understandi...

Neural network analysis of sleep stages enables efficient diagnosis of narcolepsy.

Nature communications
Analysis of sleep for the diagnosis of sleep disorders such as Type-1 Narcolepsy (T1N) currently requires visual inspection of polysomnography records by trained scoring technicians. Here, we used neural networks in approximately 3,000 normal and abn...

Exploring the clinical features of narcolepsy type 1 versus narcolepsy type 2 from European Narcolepsy Network database with machine learning.

Scientific reports
Narcolepsy is a rare life-long disease that exists in two forms, narcolepsy type-1 (NT1) or type-2 (NT2), but only NT1 is accepted as clearly defined entity. Both types of narcolepsies belong to the group of central hypersomnias (CH), a spectrum of p...

Diagnostic value of sleep stage dissociation as visualized on a 2-dimensional sleep state space in human narcolepsy.

Journal of neuroscience methods
BACKGROUND: Type 1 narcolepsy (NT1) is characterized by symptoms believed to represent Rapid Eye Movement (REM) sleep stage dissociations, occurrences where features of wake and REM sleep are intermingled, resulting in a mixed state. We hypothesized ...

Clinical course of H1N1-vaccine-related narcolepsy.

Sleep medicine
OBJECTIVE: To follow and analyze the clinical course and quality of life of Pandemrix H1N1-vaccine-related narcolepsy (pNT1).

[Constructing a cataplexy face prediction model for narcolepsy type 1 based on ResNet-18].

Zhonghua yi xue za zhi
To establish a prediction model for the identifying of cataplexy facial features based on clinical shooting videos by using a deep learning image recognition network ResNet-18. A cross-sectional study. Twenty-five narcolepsy type 1 patients who wer...