AIMC Topic: Neoplasms

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Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification.

BMC bioinformatics
BACKGROUND: As a machine learning method with high performance and excellent generalization ability, extreme learning machine (ELM) is gaining popularity in various studies. Various ELM-based methods for different fields have been proposed. However, ...

Application of BERT to Enable Gene Classification Based on Clinical Evidence.

BioMed research international
The identification of profiled cancer-related genes plays an essential role in cancer diagnosis and treatment. Based on literature research, the classification of genetic mutations continues to be done manually nowadays. Manual classification of gene...

Leveraging TCGA gene expression data to build predictive models for cancer drug response.

BMC bioinformatics
BACKGROUND: Machine learning has been utilized to predict cancer drug response from multi-omics data generated from sensitivities of cancer cell lines to different therapeutic compounds. Here, we build machine learning models using gene expression da...

Patient generated health data and electronic health record integration in oncologic surgery: A call for artificial intelligence and machine learning.

Journal of surgical oncology
In this review, we aim to assess the current state of science in relation to the integration of patient-generated health data (PGHD) and patient-reported outcomes (PROs) into routine clinical care with a focus on surgical oncology populations. We wil...

Identification of Latent Oncogenes with a Network Embedding Method and Random Forest.

BioMed research international
Oncogene is a special type of genes, which can promote the tumor initiation. Good study on oncogenes is helpful for understanding the cause of cancers. Experimental techniques in early time are quite popular in detecting oncogenes. However, their def...

Cancer gene expression profiles associated with clinical outcomes to chemotherapy treatments.

BMC medical genomics
BACKGROUND: Machine learning (ML) methods still have limited applicability in personalized oncology due to low numbers of available clinically annotated molecular profiles. This doesn't allow sufficient training of ML classifiers that could be used f...

PeptiDesCalculator: Software for computation of peptide descriptors. Definition, implementation and case studies for 9 bioactivity endpoints.

Proteins
We present a novel Java-based program denominated PeptiDesCalculator for computing peptide descriptors. These descriptors include: redefinitions of known protein parameters to suite the peptide domain, generalization schemes for the global descriptio...

Accelerated training of bootstrap aggregation-based deep information extraction systems from cancer pathology reports.

Journal of biomedical informatics
OBJECTIVE: In machine learning, it is evident that the classification of the task performance increases if bootstrap aggregation (bagging) is applied. However, the bagging of deep neural networks takes tremendous amounts of computational resources an...

Synthesis of diagnostic quality cancer pathology images by generative adversarial networks.

The Journal of pathology
Deep learning-based computer vision methods have recently made remarkable breakthroughs in the analysis and classification of cancer pathology images. However, there has been relatively little investigation of the utility of deep neural networks to s...