AIMC Topic: Neoplasms

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A framework to create, evaluate and select synthetic datasets for survival prediction in oncology.

Computers in biology and medicine
BACKGROUND AND PURPOSE: Data-driven decision-making in radiation oncology (RO) relies on integrating real-world data effectively. Synthetic data (SD), generated through machine learning, offers a solution by mimicking real-world data without compromi...

Machine learning predictions of tumor progression: How reliable are we?

Computers in biology and medicine
BACKGROUND: Cancer continues to pose significant challenges in healthcare due to the complex nature of tumor progression. In this digital era, artificial intelligence has emerged as a powerful tool that can potentially transform multiple aspects of c...

Radiation oncology patients' perceptions of artificial intelligence and machine learning in cancer care: A multi-centre cross-sectional study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
AIM: The use of artificial intelligence (AI) and machine learning (ML) is increasingly widespread in radiation oncology. However, patient engagement to date has been poor. Respect for persons in the healthcare setting and the principle of informed co...

Advancing the frontier of artificial intelligence on emerging technologies to redefine cancer diagnosis and care.

Computers in biology and medicine
BACKGROUND: Artificial Intelligence (AI) is capable of revolutionizing cancer therapy and advancing precision oncology via integrating genomics data and digitized health information. AI applications show promise in cancer prediction, prognosis, and t...

A novel machine learning-based workflow to capture intra-patient heterogeneity through transcriptional multi-label characterization and clinically relevant classification.

Journal of biomedical informatics
OBJECTIVES: Patient classification into specific molecular subtypes is paramount in biomedical research and clinical practice to face complex, heterogeneous diseases. Existing methods, especially for gene expression-based cancer subtyping, often simp...

MORPSO_ECD+ELM: A Unified Framework for Gene Selection and Cancer Classification.

IEEE journal of biomedical and health informatics
Gene selection and cancer classification are inherently multi-objective tasks that require balancing competing objectives, such as maximizing classification accuracy while minimizing irrelevant or redundant genes. Existing methods often optimize a si...

AGCLNDA: Enhancing the Prediction of ncRNA-Drug Resistance Association Using Adaptive Graph Contrastive Learning.

IEEE journal of biomedical and health informatics
Non-coding RNAs (ncRNAs), which do not encode proteins, have been implicated in chemotherapy resistance in cancer treatment. Given the high costs and time requirements of traditional biological experiments, there is an increasing need for computation...

Intelligent deep learning model for targeted cancer drug delivery.

Scientific reports
Nanotechnology and information communication technology (ICT) are being combined to develop innovative drug delivery systems for targeted sites, such as tumor cells. The particulate targeted drug delivery (PTDD) system involves drugs containing nanop...

MLOmics: Cancer Multi-Omics Database for Machine Learning.

Scientific data
Framing the investigation of diverse cancers as a machine learning problem has recently shown significant potential in multi-omics analysis and cancer research. Empowering these successful machine learning models are the high-quality training dataset...

Comprehensive biobanking strategy with clinical impact at the European Cancer Moonshot Lund Center.

Journal of proteomics
This white paper presents a comprehensive biobanking framework developed at the European Cancer Moonshot Lund Center that merges rigorous sample handling, advanced automation, and multi-omic analyses to accelerate precision oncology. Tumor and blood-...