AIMC Topic: Nerve Tissue Proteins

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Integrative PPI network and random forest analysis identifies KIF4A, TOP2A, and ASPM protein macromolecules as novel protein biomarkers in renal carcinoma pathogenesis.

International journal of biological macromolecules Jun 1, 2025
The pathogenesis of kidney cancer is not fully understood, so there is an urgent need to identify new biomarkers to improve diagnosis and treatment. The study identified KIF4A, TOP2A and ASPM as novel protein biomarkers for renal cancer and explored ...
Kidney Neoplasms Carcinoma, Renal Cell Random Forest DNA Topoisomerases, Type II Poly-ADP-Ribose Binding Proteins Kinesins Gene Expression Regulation, Neoplastic Epithelial-Mesenchymal Transition Nerve Tissue Proteins Protein Interaction Maps Computational Biology Cell Line, Tumor Prognosis Humans Biomarkers, Tumor Gene Expression Profiling
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An enhanced workflow for variant interpretation in UniProtKB/Swiss-Prot improves consistency and reuse in ClinVar.

Database : the journal of biological databases and curation Jan 1, 2019
Personalized genomic medicine depends on integrated analyses that combine genetic and phenotypic data from individual patients with reference knowledge of the functional and clinical significance of sequence variants. Sources of this reference knowle...
Nerve Tissue Proteins Workflow Databases, Protein Copper-Transporting ATPases Zinc Finger Protein Gli3 Genetic Variation Knowledge Bases
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CAMELOT: A machine learning approach for coarse-grained simulations of aggregation of block-copolymeric protein sequences.

The Journal of chemical physics Dec 28, 2015
We report the development and deployment of a coarse-graining method that is well suited for computer simulations of aggregation and phase separation of protein sequences with block-copolymeric architectures. Our algorithm, named CAMELOT for Coarse-g...
Humans Amino Acid Sequence Huntingtin Protein Molecular Sequence Data Computer Simulation Nerve Tissue Proteins Machine Learning
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Correlation of Brain Neuropeptide (Nesfatin-1 and Orexin-A) Concentrations with Anthropometric and Biochemical Parameters in Malnourished Children.

Journal of clinical research in pediatric endocrinology Sep 1, 2015
OBJECTIVE: Malnutrition continues to be a leading cause of stunted growth in many countries. This study aimed to investigate serum nesfatin-1 and orexin-A levels in underweight children and the potential correlations of these levels with anthropometr...
Anthropometry Child Nutrition Disorders Multivariate Analysis Vitamin B 12 Body Height Body Weight Body Mass Index Calcium-Binding Proteins Nerve Tissue Proteins Nucleobindins Enzyme-Linked Immunosorbent Assay Orexins Thyroxine Female Case-Control Studies DNA-Binding Proteins Thyrotropin Male Humans Child Child, Preschool
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