AIMC Topic: Neural Pathways
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Abnormal amygdala functional connectivity and deep learning classification in multifrequency bands in autism spectrum disorder: A multisite functional magnetic resonance imaging study.
Human brain mapping
Nov 8, 2022
Previous studies have explored resting-state functional connectivity (rs-FC) of the amygdala in patients with autism spectrum disorder (ASD). However, it remains unclear whether there are frequency-specific FC alterations of the amygdala in ASD and w...
Constructing neural network models from brain data reveals representational transformations linked to adaptive behavior.
Nature communications
Feb 3, 2022
The human ability to adaptively implement a wide variety of tasks is thought to emerge from the dynamic transformation of cognitive information. We hypothesized that these transformations are implemented via conjunctive activations in "conjunction hu...
Structural and functional brain networks of individual differences in trait anger and anger control: An unsupervised machine learning study.
The European journal of neuroscience
Dec 27, 2021
The ability to experience, use and eventually control anger is crucial to maintain well-being and build healthy relationships. Despite its relevance, the neural mechanisms behind individual differences in experiencing and controlling anger are poorly...
Structure can predict function in the human brain: a graph neural network deep learning model of functional connectivity and centrality based on structural connectivity.
Brain structure & function
Oct 11, 2021
Although functional connectivity and associated graph theory measures (e.g., centrality; how centrally important to the network a region is) are widely used in brain research, the full extent to which these functional measures are related to the unde...
Systematic review of Pharmacogenomics Knowledgebase evidence for pharmacogenomic links to the dopamine reward pathway for heroin dependence.
Pharmacogenomics
Aug 23, 2021
Genetics play an important role in opioid use disorder (OUD); however, few specific gene variants have been identified. Therefore, there is a need to further understand the pharmacogenomics influences on the pharmacodynamics of opioids. The Pharmacog...
Structured patterns of activity in pulse-coupled oscillator networks with varied connectivity.
PloS one
Aug 11, 2021
Identifying coordinated activity within complex systems is essential to linking their structure and function. We study collective activity in networks of pulse-coupled oscillators that have variable network connectivity and integrate-and-fire dynamic...
A convolutional neural network for estimating synaptic connectivity from spike trains.
Scientific reports
Jun 8, 2021
The recent increase in reliable, simultaneous high channel count extracellular recordings is exciting for physiologists and theoreticians because it offers the possibility of reconstructing the underlying neuronal circuits. We recently presented a me...
Intranasal vasopressin modulates resting state brain activity across multiple neural systems: Evidence from a brain imaging machine learning study.
Neuropharmacology
Apr 11, 2021
Arginine vasopressin (AVP), a neuropeptide with widespread receptors in brain regions important for socioemotional processing, is critical in regulating various mammalian social behavior and emotion. Although a growing body of task-based brain imagin...
Likelihood approximation networks (LANs) for fast inference of simulation models in cognitive neuroscience.
eLife
Apr 6, 2021
In cognitive neuroscience, computational modeling can formally adjudicate between theories and affords quantitative fits to behavioral/brain data. Pragmatically, however, the space of plausible generative models considered is dramatically limited by ...
Modulation of the dynamics of cerebellar Purkinje cells through the interaction of excitatory and inhibitory feedforward pathways.
PLoS computational biology
Feb 10, 2021
The dynamics of cerebellar neuronal networks is controlled by the underlying building blocks of neurons and synapses between them. For which, the computation of Purkinje cells (PCs), the only output cells of the cerebellar cortex, is implemented thro...
Neural Pathways
Normal Distribution
Synaptic Transmission
Interneurons
Neurons
Signal Transduction
Neural Networks, Computer
Humans
Cerebellum
Purkinje Cells
Neuronal Plasticity
Computer Simulation
Excitatory Postsynaptic Potentials
Models, Neurological
Animals
Synapses
Cerebellar Cortex
Action Potentials
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