Biochemical and biophysical research communications
33839415
Acquiring events massively from single-molecule force spectroscopy (SMFS) experiments, which is crucial for revealing important biophysical information, is usually not straightforward. A significant amount of human labor is usually required to identi...
Optical microrobotics is an emerging field that has the potential to improve upon current optical tweezer studies through avenues such as limiting the exposure of biological molecules of interest to laser radiation and overcoming the current limitati...
Rapid identification of marine microorganisms is critical in marine ecology, and Raman spectroscopy is a promising means to achieve this. Single cell Raman spectra contain the biochemical profile of a cell, which can be used to identify cell phenotyp...
We report a new method for the rapid identification of pathogenic bacterial species at the single-cell level that combines laser tweezers Raman spectroscopy (LTRS) with deep learning (DL). LTRS can accurately measure single-cell Raman spectra (scRS) ...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
36527970
Accurately, rapidly, and noninvasively identifying Bacillus spores can greatly contribute to controlling a plenty of infectious diseases. Laser tweezers Raman spectroscopy (LTRS) has confirmed to be a powerful tool for studying Bacillus spores at a s...
Optical tweezers exert a strong trapping force on cells, making it crucial to analyze the movement of trapped cells. The rotation of cells plays a significant role in their swimming patterns, such as in sperm cells. We proposed a fast deep-learning-b...
Marine bacteria have been considered as important participants in revealing various carbon/sulfur/nitrogen cycles of marine ecosystem. Thus, how to accurately identify rare marine bacteria without a culture process is significant and valuable. In thi...
In-vitro blood purification is essential to a wide range of medical treatments, requiring fine-grained analysis and precise separation of blood components. Despite existing methods that can extract specific components from blood by size or by magneti...
The microbiome represents the natural presence of microorganisms, and exploring, understanding, and leveraging its functions will bring about significant breakthroughs in life sciences and applications. Raman-activated cell sorting (RACS) enables the...
is a leading foodborne pathogen that may enter a viable but nonculturable (VBNC) state to survive under environmental stresses, posing a significant health concern. VBNC cells can evade conventional culture-based detection methods, while viability-b...