AI Medical Compendium Topic

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High throughput automated detection of axial malformations in Medaka embryo.

Computers in biology and medicine
Fish embryo models are widely used as screening tools to assess the efficacy and/or toxicity of chemicals. This assessment involves the analysis of embryo morphological abnormalities. In this article, we propose a multi-scale pipeline to allow automa...

Machine Learning Methods for Automated Quantification of Ventricular Dimensions.

Zebrafish
Medaka () and zebrafish () contribute substantially to our understanding of the genetic and molecular etiology of human cardiovascular diseases. In this context, the quantification of important cardiac functional parameters is fundamental. We have de...

Deep learning-enhanced light-field imaging with continuous validation.

Nature methods
Visualizing dynamic processes over large, three-dimensional fields of view at high speed is essential for many applications in the life sciences. Light-field microscopy (LFM) has emerged as a tool for fast volumetric image acquisition, but its effect...

The developmental and evolutionary characteristics of transcription factor binding site clustered regions based on an explainable machine learning model.

Nucleic acids research
Gene expression is temporally and spatially regulated by the interaction of transcription factors (TFs) and cis-regulatory elements (CREs). The uneven distribution of TF binding sites across the genome poses challenges in understanding how this distr...