AIMC Topic: Pharmacogenetics
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Ensembled machine learning framework for drug sensitivity prediction.
IET systems biology
Feb 1, 2020
Drug sensitivity prediction is one of the critical tasks involved in drug designing and discovery. Recently several online databases and consortiums have contributed to providing open access to pharmacogenomic data. These databases have helped in dev...
Integration of machine learning and pharmacogenomic biomarkers for predicting response to antidepressant treatment: can computational intelligence be used to augment clinical assessments?
Pharmacogenomics
Sep 1, 2019
PreMedKB: an integrated precision medicine knowledgebase for interpreting relationships between diseases, genes, variants and drugs.
Nucleic acids research
Jan 8, 2019
One important aspect of precision medicine aims to deliver the right medicine to the right patient at the right dose at the right time based on the unique 'omics' features of each individual patient, thus maximizing drug efficacy and minimizing adver...
L1000FWD: fireworks visualization of drug-induced transcriptomic signatures.
Bioinformatics (Oxford, England)
Jun 15, 2018
MOTIVATION: As part of the NIH Library of Integrated Network-based Cellular Signatures program, hundreds of thousands of transcriptomic signatures were generated with the L1000 technology, profiling the response of human cell lines to over 20 000 sma...
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