AIMC Topic: Phenotype

Clear Filters Showing 311 to 320 of 918 articles

Construction of genetic classification model for coronary atherosclerosis heart disease using three machine learning methods.

BMC cardiovascular disorders Feb 12, 2022
BACKGROUND: Although the diagnostic method for coronary atherosclerosis heart disease (CAD) is constantly innovated, CAD in the early stage is still missed diagnosis for the absence of any symptoms. The gene expression levels varied during disease de...
Databases, Genetic Predictive Value of Tests Coronary Artery Disease Models, Genetic Support Vector Machine Machine Learning Phenotype Transcriptome Genetic Predisposition to Disease Gene Expression Profiling Humans
View on PubMed DOI

GestaltMatcher facilitates rare disease matching using facial phenotype descriptors.

Nature genetics Feb 10, 2022
Many monogenic disorders cause a characteristic facial morphology. Artificial intelligence can support physicians in recognizing these patterns by associating facial phenotypes with the underlying syndrome through training on thousands of patient pho...
Phenotype Face Rare Diseases Neural Networks, Computer Artificial Intelligence Humans
View on PubMed DOI

PDGNet: Predicting Disease Genes Using a Deep Neural Network With Multi-View Features.

IEEE/ACM transactions on computational biology and bioinformatics Feb 3, 2022
The knowledge of phenotype-genotype associations is crucial for the understanding of disease mechanisms. Numerous studies have focused on developing efficient and accurate computing approaches to predict disease genes. However, owing to the sparsenes...
Neural Networks, Computer Feedback Computational Biology Software Phenotype
View on PubMed DOI

Network biology and artificial intelligence drive the understanding of the multidrug resistance phenotype in cancer.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy Jan 28, 2022
Globally with over 10 million deaths per year, cancer is the most transversal disease across countries, cultures, and ethnicities, affecting both developed and developing regions. Tumorigenesis is dynamically altered by distinct events and can be let...
Biology Drug Resistance, Multiple Humans Phenotype Neoplasms Artificial Intelligence
View on PubMed DOI

Marker effects and heritability estimates using additive-dominance genomic architectures via artificial neural networks in Coffea canephora.

PloS one Jan 26, 2022
Many methodologies are used to predict the genetic merit in animals and plants, but some of them require priori assumptions that may increase the complexity of the model. Artificial neural network (ANN) has advantage to not require priori assumptions...
Neural Networks, Computer Phenotype Genomics Models, Genetic Polymorphism, Single Nucleotide Genome, Plant Genetic Markers Genotype Coffea
View on PubMed DOI

Machine learning accurately predicts the multivariate performance phenotype from morphology in lizards.

PloS one Jan 21, 2022
Completing the genotype-to-phenotype map requires rigorous measurement of the entire multivariate organismal phenotype. However, phenotyping on a large scale is not feasible for many kinds of traits, resulting in missing data that can also cause prob...
Multivariate Analysis Lizards Animals Phylogeny Machine Learning Phenotype
View on PubMed DOI

PhenoApt leverages clinical expertise to prioritize candidate genes via machine learning.

American journal of human genetics Jan 20, 2022
In recent years, exome sequencing (ES) has shown great utility in the diagnoses of Mendelian disorders. However, after rigorous filtering, a typical ES analysis still involves the interpretation of hundreds of variants, which greatly hinders the rapi...
Cohort Studies Genotype Databases, Genetic Genetic Testing Computational Biology Machine Learning Software Phenotype Humans Exome Microcephaly Hearing Loss, Sensorineural Nystagmus, Congenital Intellectual Disability Scoliosis Genetic Diseases, Inborn Exome Sequencing
View on PubMed DOI

Insights into cell classification based on combination of multiple cellular mechanical phenotypes by using machine learning algorithm.

Journal of the mechanical behavior of biomedical materials Jan 19, 2022
Although cellular elastic property (CEP, also known as cellular elastic modulus) has been frequently reported as a biomarker to distinguish some cancerous cells from their benign counterparts, it cannot be adopted as a universal hallmark to be applie...
Algorithms Humans Phenotype Neoplasms Prognosis Machine Learning
View on PubMed DOI

Evidence for distinct neuro-metabolic phenotypes in humans.

NeuroImage Jan 13, 2022
Advances in magnetic resonance imaging have shown how individual differences in the structure and function of the human brain relate to health and cognition. The relationship between individual differences and the levels of neuro-metabolites, however...
Magnetic Resonance Spectroscopy Biological Variation, Population Magnetic Resonance Imaging Gyrus Cinguli Phenotype Female Male Support Vector Machine Adult Humans
View on PubMed DOI

Bringing biological ARDS phenotypes to the bedside with machine-learning-based classifiers.

The Lancet. Respiratory medicine Jan 10, 2022
Humans Respiratory Distress Syndrome Area Under Curve Machine Learning Phenotype
View on PubMed DOI
Popular Topics
Recent Journals