AIMC Topic: Precision Medicine

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Artificial intelligence and digital biomarker in precision pathology guiding immune therapy selection and precision oncology.

Cancer reports (Hoboken, N.J.)
BACKGROUND: The currently available immunotherapies already changed the strategy how many cancers are treated from first to last line. Understanding even the most complex heterogeneity in tumor tissue and mapping the spatial cartography of the tumor ...

Artificial Intelligence in Brain Tumor Imaging: A Step toward Personalized Medicine.

Current oncology (Toronto, Ont.)
The application of artificial intelligence (AI) is accelerating the paradigm shift towards patient-tailored brain tumor management, achieving optimal onco-functional balance for each individual. AI-based models can positively impact different stages ...

Predicting gene mutation status via artificial intelligence technologies based on multimodal integration (MMI) to advance precision oncology.

Seminars in cancer biology
Personalized treatment strategies for cancer frequently rely on the detection of genetic alterations which are determined by molecular biology assays. Historically, these processes typically required single-gene sequencing, next-generation sequencing...

Artificial Intelligence and Machine Learning Approaches to Facilitate Therapeutic Drug Management and Model-Informed Precision Dosing.

Therapeutic drug monitoring
BACKGROUND: Therapeutic drug monitoring (TDM) and model-informed precision dosing (MIPD) have greatly benefitted from computational and mathematical advances over the past 60 years. Furthermore, the use of artificial intelligence (AI) and machine lea...

Integration of artificial intelligence in lung cancer: Rise of the machine.

Cell reports. Medicine
The goal of oncology is to provide the longest possible survival outcomes with the therapeutics that are currently available without sacrificing patients' quality of life. In lung cancer, several data points over a patient's diagnostic and treatment ...

Precision Medicine in Glaucoma: Artificial Intelligence, Biomarkers, Genetics and Redox State.

International journal of molecular sciences
Glaucoma is a multifactorial neurodegenerative illness requiring early diagnosis and strict monitoring of the disease progression. Current exams for diagnosis and prognosis are based on clinical examination, intraocular pressure (IOP) measurements, v...

Annotation-Free Deep Learning-Based Prediction of Thyroid Molecular Cancer Biomarker BRAF (V600E) from Cytological Slides.

International journal of molecular sciences
Thyroid cancer is the most common endocrine cancer. Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all thyroid cancers arising from follicular cells. Fine needle aspiration cytology (FNAC) is a non-invasive method regar...

Current Role of Delta Radiomics in Head and Neck Oncology.

International journal of molecular sciences
The latest developments in the management of head and neck cancer show an increasing trend in the implementation of novel approaches using artificial intelligence for better patient stratification and treatment-related risk evaluation. Radiomics, or ...

[Future perspectives in surgery from a German point of view].

Chirurgie (Heidelberg, Germany)
In this article two aspects of the topic of future perspectives in surgery from a German point of view are discussed: firstly, topics of healthcare policy, such as upcoming alterations of the healthcare system, including required minimum quantities w...