AIMC Topic: Protein Processing, Post-Translational

Clear Filters Showing 71 to 80 of 136 articles

Prediction and functional analysis of prokaryote lysine acetylation site by incorporating six types of features into Chou's general PseAAC.

Journal of theoretical biology Oct 23, 2018
Lysine acetylation is one of the most important types of protein post-translational modifications (PTM) that are widely involved in cellular regulatory processes. To fully understand the regulatory mechanism of acetylation, identification of acetylat...
Computational Biology Support Vector Machine Protein Processing, Post-Translational Bacteria Acetylation Lysine Binding Sites Prokaryotic Cells Bacterial Proteins Datasets as Topic Species Specificity
View on PubMed DOI

A Hybrid Deep Learning Model for Predicting Protein Hydroxylation Sites.

International journal of molecular sciences Sep 18, 2018
Protein hydroxylation is one type of post-translational modifications (PTMs) playing critical roles in human diseases. It is known that protein sequence contains many uncharacterized residues of proline and lysine. The question that needs to be answe...
Hydroxylation Hydroxylysine Humans Models, Biological Protein Processing, Post-Translational Neural Networks, Computer Hydroxyproline Deep Learning Proteins
View on PubMed DOI

SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites.

Scientific reports Jul 26, 2018
Protein S-sulfenylation, which results from oxidation of free thiols on cysteine residues, has recently emerged as an important post-translational modification that regulates the structure and function of proteins involved in a variety of physiologic...
ROC Curve Computational Biology Support Vector Machine Oxidation-Reduction Protein Processing, Post-Translational Sulfhydryl Compounds Proteins Cysteine
View on PubMed DOI

Predicting lysine-malonylation sites of proteins using sequence and predicted structural features.

Journal of computational chemistry May 14, 2018
Malonylation is a recently discovered post-translational modification (PTM) in which a malonyl group attaches to a lysine (K) amino acid residue of a protein. In this work, a novel machine learning model, SPRINT-Mal, is developed to predict malonylat...
Mice Protein Processing, Post-Translational Molecular Structure Humans Machine Learning Animals Hominidae Saccharopolyspora Bacterial Proteins Lysine Malonates
View on PubMed DOI

Prediction of lysine glutarylation sites by maximum relevance minimum redundancy feature selection.

Analytical biochemistry Apr 8, 2018
Lysine glutarylation is new type of protein acylation modification in both prokaryotes and eukaryotes. To better understand the molecular mechanism of glutarylation, it is important to identify glutarylated substrates and their corresponding glutaryl...
Protein Processing, Post-Translational Proteins Lysine Glutarates Sequence Analysis, Protein Acylation Software Support Vector Machine
View on PubMed DOI

New insights into the efficiency of thymol synergistic effect with p-cymene in inhibiting advanced glycation end products: A multi-way analysis based on spectroscopic and electrochemical methods in combination with molecular docking study.

Journal of pharmaceutical and biomedical analysis Dec 24, 2017
Protein glycation in the body is one of the main reasons of diabetes complications. The electrochemical studies on the inhibitory mechanism of glycation are rather scarce. Thus, it is important to investigate the role of electrochemistry in the glyca...
Spectrophotometry, Ultraviolet Lysine Binding Sites Electrochemical Techniques Cymenes Hypoglycemic Agents Serum Albumin, Bovine Kinetics Thymol Monoterpenes Glycation End Products, Advanced Protein Processing, Post-Translational Drug Synergism Molecular Docking Simulation Arginine Structure-Activity Relationship Protein Binding Protein Conformation Glycosylation
View on PubMed DOI

EPuL: An Enhanced Positive-Unlabeled Learning Algorithm for the Prediction of Pupylation Sites.

Molecules (Basel, Switzerland) Sep 5, 2017
Protein pupylation is a type of post-translation modification, which plays a crucial role in cellular function of bacterial organisms in prokaryotes. To have a better insight of the mechanisms underlying pupylation an initial, but important, step is ...
Databases, Protein Computational Biology Protein Processing, Post-Translational Proteins Algorithms Protein Binding Machine Learning Software
View on PubMed DOI

Prediction of lysine propionylation sites using biased SVM and incorporating four different sequence features into Chou's PseAAC.

Journal of molecular graphics & modelling Jul 25, 2017
Lysine propionylation is an important and common protein acylation modification in both prokaryotes and eukaryotes. To better understand the molecular mechanism of propionylation, it is important to identify propionylated substrates and their corresp...
Algorithms Reproducibility of Results Acetylation Lysine Position-Specific Scoring Matrices Peptides Computational Biology Support Vector Machine Protein Processing, Post-Translational Amino Acids Amino Acid Sequence
View on PubMed DOI

S-SulfPred: A sensitive predictor to capture S-sulfenylation sites based on a resampling one-sided selection undersampling-synthetic minority oversampling technique.

Journal of theoretical biology Apr 12, 2017
Protein S-sulfenylation is a reversible post-translational modification involving covalent attachment of hydroxide to the thiol group of cysteine residues, which is involved in various biological processes including cell signaling, response to stress...
Protein Processing, Post-Translational Databases, Protein Cysteine Sequence Analysis, Protein Software Support Vector Machine
View on PubMed DOI

predCar-site: Carbonylation sites prediction in proteins using support vector machine with resolving data imbalanced issue.

Analytical biochemistry Mar 9, 2017
The carbonylation is found as an irreversible post-translational modification and considered a biomarker of oxidative stress. It plays major role not only in orchestrating various biological processes but also associated with some diseases such as Al...
Sequence Analysis, Protein Proteins Models, Biological Protein Carbonylation Humans Support Vector Machine Algorithms Software Protein Processing, Post-Translational Computational Biology
View on PubMed DOI
Popular Topics
Recent Journals