AIMC Topic: Sulfhydryl Compounds
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Bioinspired Iron Porphyrin Covalent Organic Frameworks-Based Nanozymes Sensor Array: Machine Learning-Assisted Identification and Detection of Thiols.
ACS applied materials & interfaces
Dec 12, 2024
Given the crucial role of thiols in maintaining normal physiological functions, it is essential to establish a high-throughput and sensitive analytical method to identify and quantify various thiols accurately. Inspired by the iron porphyrin active c...
Deep learning-assisted surface-enhanced Raman spectroscopy detection of intracellular reactive oxygen species.
Talanta
Nov 15, 2024
Realizing the intelligent analysis of the intracellular reactive oxygen species (ROS) is beneficial to quick diagnosis of diseases. Herein, surface-enhanced Raman spectroscopy (SERS) technology was combined with deep learning to establish a smart det...
Thiol modified bimodal mesoporous silica nanoparticles for removal and determination toxic vanadium from air and human biological samples in petrochemical workers.
NanoImpact
Jun 24, 2021
Investigation of exposure to toxic vanadium (V) in petrochemical workers is very important for human health, and it must be removed and determined in workplace air and human biological samples. In this research, the enriched adsorbent based on the th...
Cautionary Guidelines for Machine Learning Studies with Combinatorial Datasets.
ACS combinatorial science
Oct 1, 2020
Regression modeling is becoming increasingly prevalent in organic chemistry as a tool for reaction outcome prediction and mechanistic interrogation. Frequently, to acquire the requisite amount of data for such studies, researchers employ combinatoria...
Antioxidant and Anti-inflammatory Diagnostic Biomarkers in Multiple Sclerosis: A Machine Learning Study.
Molecular neurobiology
Jan 22, 2020
An imbalance of inflammatory/anti-inflammatory and oxidant/antioxidant molecules has been implicated in the demyelination and axonal damage in multiple sclerosis (MS). The current study aimed to evaluate the plasma levels of tumor necrosis factor (TN...
Advanced Oxidation Protein Products
Nitrosative Stress
Receptors, Tumor Necrosis Factor
Nitric Oxide
Inflammation
Support Vector Machine
Oxidation-Reduction
Sulfhydryl Compounds
Multiple Sclerosis
Adiponectin
Male
Middle Aged
Oxidative Stress
Antioxidants
Female
Adult
Sensitivity and Specificity
Humans
Neural Networks, Computer
Tumor Necrosis Factor-alpha
Biomarkers
Smart Plasmonic Nanorobot for Real-Time Monitoring Cytochrome c Release and Cell Acidification in Apoptosis during Electrostimulation.
Analytical chemistry
Dec 4, 2018
Cytochrome c (Cyt c) release and cellular pH change are two important mediators of apoptosis. Effective methods to regulate or monitor such two events are therefore highly desired for apoptosis research and cancer cell therapy. Herein, we exploited e...
SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites.
Scientific reports
Jul 26, 2018
Protein S-sulfenylation, which results from oxidation of free thiols on cysteine residues, has recently emerged as an important post-translational modification that regulates the structure and function of proteins involved in a variety of physiologic...
Label-free impedimetric glycan biosensor for quantitative evaluation interactions between pathogenic bacteria and mannose.
Biosensors & bioelectronics
Dec 2, 2017
In order to understanding the pathogenic mechanism of infectious diseases, it was important to study the selective recognition and interaction between pathogenic bacteria and host cells. In this paper, a novel electrochemical impedance biosensor was ...
Manipulation of Biomolecule-Modified Liquid-Metal Blobs.
Angewandte Chemie (International ed. in English)
Oct 2, 2017
Soft and deformable liquid metals (LMs) are building components in various systems related to uncertain and dynamic task environments. Herein we describe the development of a biomolecule-triggered external-manipulation method involving LM conjugates ...
Molecule-Responsive SERS Sensors for Urine Diagnosis of Kidney Diseases Enhanced by Neural Networks.
Analytical chemistry
Jul 1, 2025
Early diagnosis of kidney disease is crucial for treatment and prognosis. Compared with kidney biopsy, a noninvasive urine-based diagnosis method of kidney disease can be more convenient and less painful for patients. Urine is closely associated with...
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