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Pyramidal Cells

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Long-range recruitment of Martinotti cells causes surround suppression and promotes saliency in an attractor network model.

Frontiers in neural circuits
Although the importance of long-range connections for cortical information processing has been acknowledged for a long time, most studies focused on the long-range interactions between excitatory cortical neurons. Inhibitory interneurons play an impo...

A Lognormal Recurrent Network Model for Burst Generation during Hippocampal Sharp Waves.

The Journal of neuroscience : the official journal of the Society for Neuroscience
The strength of cortical synapses distributes lognormally, with a long tail of strong synapses. Various properties of neuronal activity, such as the average firing rates of neurons, the rate and magnitude of spike bursts, the magnitude of population ...

Coherent and intermittent ensemble oscillations emerge from networks of irregular spiking neurons.

Journal of neurophysiology
Local field potential (LFP) recordings from spatially distant cortical circuits reveal episodes of coherent gamma oscillations that are intermittent, and of variable peak frequency and duration. Concurrently, single neuron spiking remains largely irr...

Structured Pyramidal Neural Networks.

International journal of neural systems
The Pyramidal Neural Networks (PNN) are an example of a successful recently proposed model inspired by the human visual system and deep learning theory. PNNs are applied to computer vision and based on the concept of receptive fields. This paper prop...

Variable synaptic strengths controls the firing rate distribution in feedforward neural networks.

Journal of computational neuroscience
Heterogeneity of firing rate statistics is known to have severe consequences on neural coding. Recent experimental recordings in weakly electric fish indicate that the distribution-width of superficial pyramidal cell firing rates (trial- and time-ave...

Cumulative inhibition in neural networks.

Cognitive processing
We show how a multi-resolution network can model the development of acuity and coarse-to-fine processing in the mammalian visual cortex. The network adapts to input statistics in an unsupervised manner, and learns a coarse-to-fine representation by u...

Phase relations of theta oscillations in a computer model of the hippocampal CA1 field: Key role of Schaffer collaterals.

Neural networks : the official journal of the International Neural Network Society
The hippocampal theta rhythm (4-12 Hz) is one of the most important electrophysiological processes in the hippocampus, it participates in cognitive hippocampal functions, such as navigation in space, novelty detection, and declarative memory. We use ...

Reducing variability in motor cortex activity at a resting state by extracellular GABA for reliable perceptual decision-making.

Journal of computational neuroscience
Interaction between sensory and motor cortices is crucial for perceptual decision-making, in which intracortical inhibition might have an important role. We simulated a neural network model consisting of a sensory network (N) and a motor network (N) ...

An efficient analytical reduction of detailed nonlinear neuron models.

Nature communications
Detailed conductance-based nonlinear neuron models consisting of thousands of synapses are key for understanding of the computational properties of single neurons and large neuronal networks, and for interpreting experimental results. Simulations of ...

Endocannabinoid degradation inhibitors ameliorate neuronal and synaptic alterations following traumatic brain injury.

Journal of neurophysiology
Our previous work showed that lateral fluid percussion injury to the sensorimotor cortex (SMC) of anesthetized rats increased neuronal synaptic hyperexcitability in layer 5 (L5) neurons in ex vivo brain slices 10 days postinjury. Furthermore, endocan...