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Interneurons

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Neural Interactions in Developing Rhythmogenic Spinal Networks: Insights From Computational Modeling.

Frontiers in neural circuits
The mechanisms involved in generation of rhythmic locomotor activity in the mammalian spinal cord remain poorly understood. These mechanisms supposedly rely on both intrinsic properties of constituting neurons and interactions between them. A subset ...

Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neural network.

Chaos (Woodbury, N.Y.)
Sensory information is believed to be encoded in neuronal spikes using two different neural codes, the rate code (spike firing rate) and the temporal code (precisely-timed spikes). Since the sensory cortex has a highly hierarchical feedforward struct...

A Systematic Evaluation of Interneuron Morphology Representations for Cell Type Discrimination.

Neuroinformatics
Quantitative analysis of neuronal morphologies usually begins with choosing a particular feature representation in order to make individual morphologies amenable to standard statistics tools and machine learning algorithms. Many different feature rep...

Empirically constrained network models for contrast-dependent modulation of gamma rhythm in V1.

NeuroImage
Gamma oscillations are thought to play a key role in neuronal network function and neuronal communication, yet the underlying generating mechanisms have not been fully elucidated to date. At least partly, this may be due to the fact that even in simp...

Modulation of the dynamics of cerebellar Purkinje cells through the interaction of excitatory and inhibitory feedforward pathways.

PLoS computational biology
The dynamics of cerebellar neuronal networks is controlled by the underlying building blocks of neurons and synapses between them. For which, the computation of Purkinje cells (PCs), the only output cells of the cerebellar cortex, is implemented thro...

The CPGs for Limbed Locomotion-Facts and Fiction.

International journal of molecular sciences
The neuronal networks that generate locomotion are well understood in swimming animals such as the lamprey, zebrafish and tadpole. The networks controlling locomotion in tetrapods remain, however, still enigmatic with an intricate motor pattern requi...

Coordination of top-down influence on V1 responses by interneurons and brain rhythms.

Bio Systems
Top-down processing in neocortex underlies functions such as prediction, expectation, and attention. Visual systems have much feedback connection that carries information of behavioral context. Top-down signals along feedback pathways modulate the re...

Flexible gating between subspaces in a neural network model of internally guided task switching.

Nature communications
Behavioral flexibility relies on the brain's ability to switch rapidly between multiple tasks, even when the task rule is not explicitly cued but must be inferred through trial and error. The underlying neural circuit mechanism remains poorly underst...

Memristive Circuit Implementation of Caenorhabditis Elegans Mechanism for Neuromorphic Computing.

IEEE transactions on neural networks and learning systems
To overcome the energy efficiency bottleneck of the von Neumann architecture and scaling limit of silicon transistors, an emerging but promising solution is neuromorphic computing, a new computing paradigm inspired by how biological neural networks h...

A deep learning strategy to identify cell types across species from high-density extracellular recordings.

Cell
High-density probes allow electrophysiological recordings from many neurons simultaneously across entire brain circuits but fail to reveal cell type. Here, we develop a strategy to identify cell types from extracellular recordings in awake animals an...