AIMC Topic: Receptors, CCR2

Clear Filters Showing 1 to 2 of 2 articles

Immune profile of the tumor microenvironment and the identification of a four-gene signature for lung adenocarcinoma.

Aging Dec 9, 2020
The composition and relative abundances of immune cells in the tumor microenvironment are key factors affecting the progression of lung adenocarcinomas (LUADs) and the efficacy of immunotherapy. Using the cancer gene expression dataset from The Cance...
Humans Prognosis Female Aged Tumor Microenvironment Biomarkers, Tumor Male Middle Aged Lung Neoplasms Gene Expression Regulation, Neoplastic Receptors, CCR2 Gene Ontology Adenocarcinoma of Lung Receptors, CCR4 Receptors, Purinergic P2 Receptors, Purinergic P2Y12
View on PubMed DOI

Cenicriviroc, a dual CCR2 and CCR5 antagonist leads to a reduction in plasma fibrotic biomarkers in persons living with HIV on antiretroviral therapy.

HIV research & clinical practice Feb 4, 2020
Chronic HIV is associated with increased inflammation and tissue fibrosis despite suppressive antiretroviral therapy (ART). Monocytes and macrophages have been implicated in the pathogenesis of fibrosis, facilitated by chemokine receptor interaction...
Humans Macrophages Biomarkers Female Male Middle Aged HIV Infections Anti-HIV Agents Cohort Studies Monocytes Inflammation Imidazoles CCR5 Receptor Antagonists Receptors, CCR2 Sulfoxides
View on PubMed DOI
Popular Topics
Recent Journals