AIMC Topic: Brain-Derived Neurotrophic Factor
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From neurotoxicity to neuroprotection: Rethinking GABAR-targeting anesthetics.
Cell biology and toxicology
Jun 14, 2025
The brain growth spurt (BGS) represents a pivotal window in neurodevelopment, defined by rapid neurogenesis, heightened synaptogenesis, and the dynamic establishment of neural networks. During this phase, heightened brain plasticity significantly enh...
Multiomic Network Analysis Identifies Dysregulated Neurobiological Pathways in Opioid Addiction.
Biological psychiatry
Nov 29, 2024
BACKGROUND: Opioid addiction is a worldwide public health crisis. In the United States, for example, opioids cause more drug overdose deaths than any other substance. However, opioid addiction treatments have limited efficacy, meaning that additional...
Effect of ethanol extract of nigella sativa L seeds and propofol on BDNF protein level as neuroplasticity and neuroprotection of traumatic brain injury in rats.
F1000Research
Sep 23, 2024
BACKGROUND: Traumatic brain injury (TBI) is a change in brain function or evidence of brain pathology caused by external mechanical forces. Brain Derived Neurotrophic Factor (BDNF) is a neurotropin that functions as a neuron protective. Nigella sativ...
Neuronal survival of DRG neurons after neurite transection in vitro promotes by nerve growth factor and brain derived neurotrophic factor.
Cellular and molecular biology (Noisy-le-Grand, France)
Dec 31, 2018
Neurotrophic factors are growth factors that promote neuronal survival, regulate synaptic function and neurotransmitter release, and promote the plasticity and growth of axons in the peripheral and central nervous systems. This study focused on the r...
Robot-assisted mechanical therapy attenuates stroke-induced limb skeletal muscle injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Nov 28, 2016
The efficacy and optimization of poststroke physical therapy paradigms is challenged in part by a lack of objective tools available to researchers for systematic preclinical testing. This work represents a maiden effort to develop a robot-assisted me...
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