OBJECTIVES: To propose an alternative solid phase extraction-gas chromatography-mass spectrometry （SPE-GC-MS） method for the sensitive determination of cathinones in human urine samples, plus methodological verification.
OBJECTIVES: To develop a liquid chromatography-tandem mass spectrometry （LC-MS/MS） analytical method for the determination of oleandrin in blood and liver tissues, which could be applied to the cases of death caused by oleander poisoning.
HPB : the official journal of the International Hepato Pancreato Biliary Association
Dec 24, 2018
BACKGROUND: To predict the risk and severity of acute respiratory distress syndrome (ARDS) following severe acute pancreatitis (SAP) by artificial neural networks (ANNs) model.
Journal of biomolecular structure & dynamics
Dec 24, 2018
Matrix metal proteinases-12 (MMP-12) is a hot pharmaceutical target on the treatment of many human diseases. There's a crying need for designing and finding new MMP-12 inhibitors. In this work, four machine learning approaches, support vector machine...
Journal of pharmaceutical and biomedical analysis
Dec 21, 2018
A new, rapid, simple and specific method to determine 5-chloro 8-hydroxyquinoline (5-HQ) and 5,7-dichloro 8-hydroxyquinoline (5,7-HQ) stability in swine feed was optimized and validated. A system consisting of an ACQUITY UPLC BEH C column (1.7 μm, 2....
Journal of clinical pharmacy and therapeutics
Dec 18, 2018
WHAT IS KNOWN AND OBJECTIVE: Drug-drug interactions (DDI) are frequent causes of adverse clinical drug reactions. Efforts have been directed at the early stage to achieve accurate identification of DDI for drug safety assessments, including the devel...
Ultrasound imaging remains out of reach for most pregnant women in developing countries because it requires a trained sonographer to acquire and interpret the images. We address this problem by presenting a system that can automatically estimate the ...
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
Dec 17, 2018
Diabetic retinopathy, glaucoma, and age-related macular degeneration are leading causes of vision loss and blindness worldwide. They tend to be asymptomatic in the early phase of disease and therefore require active screening programs to identify the...
Over the last four decades, there has been a pursuit for a non-invasive solution for glucose measurement, but there is not yet any viable product released. Of the many sensor modalities tried, the combination of electrical and optical measurement is ...
International journal of computer assisted radiology and surgery
Dec 14, 2018
PURPOSE: In-bed motion monitoring has become of great interest for a variety of clinical applications. Image-based approaches could be seen as a natural non-intrusive approach for this purpose; however, video devices require special challenging setti...
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