AIMC Topic: Research Design

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Estimating individualized treatment regimes from crossover designs.

Biometrics
The field of precision medicine aims to tailor treatment based on patient-specific factors in a reproducible way. To this end, estimating an optimal individualized treatment regime (ITR) that recommends treatment decisions based on patient characteri...

Natural language processing to facilitate breast cancer research and management.

The breast journal
The medical literature has been growing exponentially, and its size has become a barrier for physicians to locate and extract clinically useful information. As a promising solution, natural language processing (NLP), especially machine learning (ML)-...

Current state of science in machine learning methods for automatic infant pain evaluation using facial expression information: study protocol of a systematic review and meta-analysis.

BMJ open
INTRODUCTION: Infants can experience pain similar to adults, and improperly controlled pain stimuli could have a long-term adverse impact on their cognitive and neurological function development. The biggest challenge of achieving good infant pain co...

Spatial Lifecourse Epidemiology Reporting Standards (ISLE-ReSt) statement.

Health & place
Spatial lifecourse epidemiology is an interdisciplinary field that utilizes advanced spatial, location-based, and artificial intelligence technologies to investigate the long-term effects of environmental, behavioural, psychosocial, and biological fa...

Evolving multilayer perceptron, and factorial design for modelling and optimization of dye decomposition by bio-synthetized nano CdS-diatomite composite.

Environmental research
Design of experiment and hybrid genetic algorithm optimized multilayer perceptron (GA-MLP) artificial neural network have been employed to model and predict dye decomposition capacity of the biologically synthesized nano CdS diatomite composite. Impa...

Machine learning of physiological waveforms and electronic health record data to predict, diagnose and treat haemodynamic instability in surgical patients: protocol for a retrospective study.

BMJ open
INTRODUCTION: About 42 million surgeries are performed annually in the USA. While the postoperative mortality is less than 2%, 12% of all patients in the high-risk surgery group account for 80% of postoperative deaths. New onset of haemodynamic insta...

Added Value of Quantitative Ultrasound and Machine Learning in BI-RADS 4-5 Assessment of Solid Breast Lesions.

Ultrasound in medicine & biology
The purpose of this study was to evaluate various combinations of 13 features based on shear wave elasticity (SWE), statistical and spectral backscatter properties of tissues, along with the Breast Imaging Reporting and Data System (BI-RADS), for cla...

Data augmentation using generative adversarial networks (CycleGAN) to improve generalizability in CT segmentation tasks.

Scientific reports
Labeled medical imaging data is scarce and expensive to generate. To achieve generalizable deep learning models large amounts of data are needed. Standard data augmentation is a method to increase generalizability and is routinely performed. Generati...

Intelligent Sensing to Inform and Learn (InSTIL): A Scalable and Governance-Aware Platform for Universal, Smartphone-Based Digital Phenotyping for Research and Clinical Applications.

Journal of medical Internet research
In this viewpoint we describe the architecture of, and design rationale for, a new software platform designed to support the conduct of digital phenotyping research studies. These studies seek to collect passive and active sensor signals from partici...