AIMC Topic: Research Design

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CycleDNN - A Novel Deep Neural Network Model for CETSA Feature Prediction cross Cell Lines.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Cellular Thermal Shift Assay (CETSA) has been widely used in drug discovery, cancer cell biology, immunology, etc. One of the barriers for CETSA applications is that CETSA experiments have to be conducted on various cell lines, which is extremely tim...

Local Explanation-Based Method for Healthcare Risk Stratification.

Studies in health technology and informatics
Decision support tools in healthcare require a strong confidence in the developed Machine Learning (ML) models both in terms of performances and in their ability to provide users a deeper understanding of the underlying situation. This study presents...

Knowledge-based BERT: a method to extract molecular features like computational chemists.

Briefings in bioinformatics
Molecular property prediction models based on machine learning algorithms have become important tools to triage unpromising lead molecules in the early stages of drug discovery. Compared with the mainstream descriptor- and graph-based methods for mol...

TF-Unet:An automatic cardiac MRI image segmentation method.

Mathematical biosciences and engineering : MBE
Personalized heart models are widely used to study the mechanisms of cardiac arrhythmias and have been used to guide clinical ablation of different types of arrhythmias in recent years. MRI images are now mostly used for model building. In cardiac mo...

Translating promise into practice: a review of machine learning in suicide research and prevention.

The lancet. Psychiatry
In ever more pressured health-care systems, technological solutions offering scalability of care and better resource targeting are appealing. Research on machine learning as a technique for identifying individuals at risk of suicidal ideation, suicid...

A new MAGDM method with 2-tuple linguistic bipolar fuzzy Heronian mean operators.

Mathematical biosciences and engineering : MBE
In this article, we introduce the 2-tuple linguistic bipolar fuzzy set (2TLBFS), a new strategy for dealing with uncertainty that incorporates a 2-tuple linguistic term into bipolar fuzzy set. The 2TLBFS is a better way to deal with uncertain and imp...

Artificial intelligence in clinical research of cancers.

Briefings in bioinformatics
Several factors, including advances in computational algorithms, the availability of high-performance computing hardware, and the assembly of large community-based databases, have led to the extensive application of Artificial Intelligence (AI) in th...

LR-GNN: a graph neural network based on link representation for predicting molecular associations.

Briefings in bioinformatics
In biomedical networks, molecular associations are important to understand biological processes and functions. Many computational methods, such as link prediction methods based on graph neural networks (GNNs), have been successfully applied in discov...