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Retroelements

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A machine learning based framework to identify and classify long terminal repeat retrotransposons.

PLoS computational biology
Transposable elements (TEs) are repetitive nucleotide sequences that make up a large portion of eukaryotic genomes. They can move and duplicate within a genome, increasing genome size and contributing to genetic diversity within and across species. A...

Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia.

Nature neuroscience
Retrotransposons can cause somatic genome variation in the human nervous system, which is hypothesized to have relevance to brain development and neuropsychiatric disease. However, the detection of individual somatic mobile element insertions present...

Inpactor2: a software based on deep learning to identify and classify LTR-retrotransposons in plant genomes.

Briefings in bioinformatics
LTR-retrotransposons are the most abundant repeat sequences in plant genomes and play an important role in evolution and biodiversity. Their characterization is of great importance to understand their dynamics. However, the identification and classif...