AIMC Topic: Ribosomes
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Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli.
ACS synthetic biology
Jan 7, 2019
The field of synthetic biology aims to make the design of biological systems predictable, shrinking the huge design space to practical numbers for testing. When designing microbial cell factories, most optimization efforts have focused on enzyme and ...
LncRNA-ID: Long non-coding RNA IDentification using balanced random forests.
Bioinformatics (Oxford, England)
Aug 26, 2015
MOTIVATION: Long non-coding RNAs (lncRNAs), which are non-coding RNAs of length above 200 nucleotides, play important biological functions such as gene expression regulation. To fully reveal the functions of lncRNAs, a fundamental step is to annotate...
Exploring the potential of large language model-based chatbots in challenges of ribosome profiling data analysis: a review.
Briefings in bioinformatics
Nov 22, 2024
Ribosome profiling (Ribo-seq) provides transcriptome-wide insights into protein synthesis dynamics, yet its analysis poses challenges, particularly for nonbioinformatics researchers. Large language model-based chatbots offer promising solutions by le...
DM3Loc: multi-label mRNA subcellular localization prediction and analysis based on multi-head self-attention mechanism.
Nucleic acids research
May 7, 2021
Subcellular localization of messenger RNAs (mRNAs), as a prevalent mechanism, gives precise and efficient control for the translation process. There is mounting evidence for the important roles of this process in a variety of cellular events. Computa...
Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.
Advances in experimental medicine and biology
Jan 1, 2016
Here we propose a model of a peripheral axon with a great deal of autonomy from its cell body-the autonomous axon-but with a substantial dependence on its ensheathing Schwann cell (SC), the axon-SC unit. We review evidence in several fields and show ...
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