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An interpretable machine learning model for predicting in-hospital mortality in ICU patients with ventilator-associated pneumonia.

PloS one
BACKGROUND: Ventilator-associated pneumonia (VAP) is a common nosocomial infection in ICU, significantly associated with poor outcomes. However, there is currently a lack of reliable and interpretable tools for assessing the risk of in-hospital morta...

Machine learning algorithms to predict depression in older adults in China: a cross-sectional study.

Frontiers in public health
OBJECTIVE: The 2-fold objective of this research is to investigate machine learning's (ML) predictive value for the incidence of depression among China's older adult population and to determine the noteworthy aspects resulting in depression.

Plasma Epstein-Barr Virus DNA load for diagnostic and prognostic assessment in intestinal Epstein-Barr Virus infection.

Frontiers in cellular and infection microbiology
BACKGROUND: The prospective application of plasma Epstein-Barr virus (EBV) DNA load as a noninvasive measure of intestinal EBV infection remains unexplored. This study aims to identify ideal threshold levels for plasma EBV DNA loads in the diagnosis ...

Classification of α-thalassemia data using machine learning models.

Computer methods and programs in biomedicine
BACKGROUND: Around 7% of the global population has congenital hemoglobin disorders, with over 300,000 new cases of α-thalassemia annually. Diagnosis is costly and inaccurate in low-income regions, often relying on complete blood count (CBC) tests. Th...

Coronary health index based on immunoglobulin light chains to assess coronary heart disease risk with machine learning: a diagnostic trial.

Journal of translational medicine
BACKGROUND: Recent studies suggest a connection between immunoglobulin light chains (IgLCs) and coronary heart disease (CHD). However, current diagnostic methods using peripheral blood IgLCs levels or subtype ratios show limited accuracy for CHD, lac...

Prediction of pulmonary embolism by an explainable machine learning approach in the real world.

Scientific reports
In recent years, large amounts of researches showed that pulmonary embolism (PE) has become a common disease, and PE remains a clinical challenge because of its high mortality, high disability, high missed and high misdiagnosed rates. To address this...

Application of machine learning algorithms in an epidemiologic study of mortality.

Annals of epidemiology
PURPOSE: Epidemiologic studies are important in assessing risk factors of mortality. Machine learning (ML) is efficient in analyzing multidimensional data to unravel dependencies between risk factors and health outcomes.

Development of machine learning models for diagnostic biomarker identification and immune cell infiltration analysis in PCOS.

Journal of ovarian research
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. It is characterized by symptoms such as hyperandrogenemia, oligo or anovulation and polycystic ovarian, significantly impacting quality o...

Noninvasive diagnosis of significant liver fibrosis in patients with chronic hepatitis B using nomogram and machine learning models.

Scientific reports
This study aims to construct and validate noninvasive diagnosis models for evaluating significant liver fibrosis in patients with chronic hepatitis B (CHB). A cohort of 259 CHB patients were selected as research subjects. Through random grouping, 182...

Employing a low-code machine learning approach to predict in-hospital mortality and length of stay in patients with community-acquired pneumonia.

Scientific reports
Community-acquired pneumonia (CAP) is associated with high mortality rates and often results in prolonged hospital stays. The potential of machine learning to enhance prediction accuracy in this context is significant, yet clinicians often lack the p...