AIMC Topic: Rodentia

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A curated knowledgebase on endocrine disrupting chemicals and their biological systems-level perturbations.

The Science of the total environment
Human well-being can be affected by exposure to several chemicals in the environment. One such group is endocrine disrupting chemicals (EDCs) that can perturb the hormonal homeostasis leading to adverse health effects. In this work, we have developed...

Merging information in the entorhinal cortex: what can we learn from robotics experiments and modeling?

The Journal of experimental biology
Place recognition is a complex process involving idiothetic and allothetic information. In mammals, evidence suggests that visual information stemming from the temporal and parietal cortical areas ('what' and 'where' information) is merged at the lev...

DeepSqueak: a deep learning-based system for detection and analysis of ultrasonic vocalizations.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Rodents engage in social communication through a rich repertoire of ultrasonic vocalizations (USVs). Recording and analysis of USVs has broad utility during diverse behavioral tests and can be performed noninvasively in almost any rodent behavioral m...

Structured networks support sparse traveling waves in rodent somatosensory cortex.

Proceedings of the National Academy of Sciences of the United States of America
Neurons responding to different whiskers are spatially intermixed in the superficial layer 2/3 (L2/3) of the rodent barrel cortex, where a single whisker deflection activates a sparse, distributed neuronal population that spans multiple cortical colu...

Global and local excitation and inhibition shape the dynamics of the cortico-striatal-thalamo-cortical pathway.

Scientific reports
The cortico-striatal-thalamo-cortical (CSTC) pathway is a brain circuit that controls movement execution, habit formation and reward. Hyperactivity in the CSTC pathway is involved in obsessive compulsive disorder (OCD), a neuropsychiatric disorder ch...

Hippocampome.org: a knowledge base of neuron types in the rodent hippocampus.

eLife
Hippocampome.org is a comprehensive knowledge base of neuron types in the rodent hippocampal formation (dentate gyrus, CA3, CA2, CA1, subiculum, and entorhinal cortex). Although the hippocampal literature is remarkably information-rich, neuron proper...

Machine Learning Approaches to Classify Anatomical Regions in Rodent Brain from High Density Recordings.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Identifying different functional regions during a brain surgery is a challenging task usually performed by highly specialized neurophysiologists. Progress in this field may be used to improve in situ brain navigation and will serve as an important bu...

Improved 3D tracking and automated classification of rodents' behavioral activity using depth-sensing cameras.

Behavior research methods
Analysis of rodents' behavior/activity is of fundamental importance in many research fields. However, many behavioral experiments still rely on manual scoring, with obvious problems in reproducibility. Despite important advances in video-analysis sys...