AIMC Topic: Glutamic Acid
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Terahertz molecular vibrational sensing using 3D printed anapole meta-biosensor.
Biosensors & bioelectronics
Mar 7, 2025
Terahertz (THz) fingerprint sensing utilizes the absorption of fingerprints generated by the unique vibrational characteristics of molecules to achieve substance-specific identification. By taking full advance of the anapole mode induced-biosensor co...
Development of the autonomous lab system to support biotechnology research.
Scientific reports
Feb 24, 2025
In this study, we developed the autonomous lab (ANL), which is a system based on robotics and artificial intelligence (AI) to conduct biotechnology experiments and formulate scientific hypotheses. This system was designed with modular devices and Bay...
Hspb1 and Lgals3 in spinal neurons are closely associated with autophagy following excitotoxicity based on machine learning algorithms.
PloS one
May 10, 2024
Excitotoxicity represents the primary cause of neuronal death following spinal cord injury (SCI). While autophagy plays a critical and intricate role in SCI, the specific mechanism underlying the relationship between excitotoxicity and autophagy in S...
Computational identification of 4-carboxyglutamate sites to supplement physiological studies using deep learning.
Scientific reports
Jan 7, 2022
In biological systems, Glutamic acid is a crucial amino acid which is used in protein biosynthesis. Carboxylation of glutamic acid is a significant post-translational modification which plays important role in blood coagulation by activating prothrom...
Diagnosis of Wilson Disease and Its Phenotypes by Using Artificial Intelligence.
Biomolecules
Aug 20, 2021
WD is caused by variants disrupting copper efflux resulting in excessive copper accumulation mainly in liver and brain. The diagnosis of WD is challenged by its variable clinical course, onset, morbidity, and variant type. Currently it is diagnosed...
Copper-Transporting ATPases
Hepatolenticular Degeneration
Ceruloplasmin
DNA, Mitochondrial
Medical Informatics
Glutamic Acid
Male
Middle Aged
Diagnosis, Computer-Assisted
Fuzzy Logic
Liver
Principal Component Analysis
Copper
Mutation
Phenotype
Brain
Female
Adult
Neural Networks, Computer
Artificial Intelligence
Algorithms
Humans
Plasma d-glutamate levels for detecting mild cognitive impairment and Alzheimer's disease: Machine learning approaches.
Journal of psychopharmacology (Oxford, England)
Feb 15, 2021
BACKGROUND: d-glutamate, which is involved in N-methyl-d-aspartate receptor modulation, may be associated with cognitive ageing.
Case-Control Studies
Humans
Psychiatric Status Rating Scales
Machine Learning
Sensitivity and Specificity
Cognitive Dysfunction
Biomarkers
Chromatography, High Pressure Liquid
Male
Algorithms
Female
Diagnosis, Differential
Alzheimer Disease
Middle Aged
Aged
Glutamic Acid
Severity of Illness Index
Aged, 80 and over
Accelerating GluCEST imaging using deep learning for B correction.
Magnetic resonance in medicine
Apr 17, 2020
PURPOSE: Glutamate weighted Chemical Exchange Saturation Transfer (GluCEST) MRI is a noninvasive technique for mapping parenchymal glutamate in the brain. Because of the sensitivity to field (B ) inhomogeneity, the total acquisition time is prolonged...
Sequence-based analysis and prediction of lantibiotics: A machine learning approach.
Computational biology and chemistry
Oct 9, 2018
Lantibiotics, an important group of ribosomally synthesized peptides, represent an important arsenal of novel promising antimicrobials showing high potency in fighting against the prevalence of antibiotic resistance among microbial pathogens. However...
MultiNet PyGRAPPA: Multiple neural networks for reconstructing variable density GRAPPA (a H FID MRSI study).
NeuroImage
Aug 17, 2018
Magnetic resonance spectroscopic imaging (MRSI) is a powerful tool for mapping metabolite levels across the brain, however, it generally suffers from long scan times. This severely hinders its application in clinical settings. Additionally, the prese...
Global and local excitation and inhibition shape the dynamics of the cortico-striatal-thalamo-cortical pathway.
Scientific reports
Aug 8, 2017
The cortico-striatal-thalamo-cortical (CSTC) pathway is a brain circuit that controls movement execution, habit formation and reward. Hyperactivity in the CSTC pathway is involved in obsessive compulsive disorder (OCD), a neuropsychiatric disorder ch...
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