AIMC Topic: GABAergic Neurons
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Niuhuang jiedu prescription alleviates realgar-induced dopaminergic and GABAergic neurotoxicity in Caenorhabditis elegans.
Journal of ethnopharmacology
Apr 2, 2025
ETHNOPHARMACOLOGICAL RELEVANCE: Niuhuang Jiedu (NHJD) is a Chinese medicine prescription containing realgar (AsS), which is neurotoxic, and seven other traditional Chinese medicines (TCMs). However, whether the multiple TCMs contained in NHJD can mit...
System-level time computation and representation in the suprachiasmatic nucleus revealed by large-scale calcium imaging and machine learning.
Cell research
Apr 11, 2024
The suprachiasmatic nucleus (SCN) is the mammalian central circadian pacemaker with heterogeneous neurons acting in concert while each neuron harbors a self-sustained molecular clockwork. Nevertheless, how system-level SCN signals encode time of the ...
A Computational Model of the Brain Cortex and Its Synchronization.
BioMed research international
Oct 23, 2020
Obtaining the computational models for the functioning of the brain gives us a chance to understand the brain functionality thoroughly. This would help the development of better treatments for neurological illnesses and disorders. We created a cortic...
Unsupervised identification of states from voltage recordings of neural networks.
Journal of neuroscience methods
Feb 23, 2019
BACKGROUND: Modern techniques for multi-neuronal recording produce large amounts of data. There is no automatic procedure for the identification of states in recurrent voltage patterns.
Global and local excitation and inhibition shape the dynamics of the cortico-striatal-thalamo-cortical pathway.
Scientific reports
Aug 8, 2017
The cortico-striatal-thalamo-cortical (CSTC) pathway is a brain circuit that controls movement execution, habit formation and reward. Hyperactivity in the CSTC pathway is involved in obsessive compulsive disorder (OCD), a neuropsychiatric disorder ch...
Classifying GABAergic interneurons with semi-supervised projected model-based clustering.
Artificial intelligence in medicine
Jan 2, 2015
OBJECTIVES: A recently introduced pragmatic scheme promises to be a useful catalog of interneuron names. We sought to automatically classify digitally reconstructed interneuronal morphologies according to this scheme. Simultaneously, we sought to dis...
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