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Sample Size

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Optimizing sample size for supervised machine learning with bulk transcriptomic sequencing: a learning curve approach.

Briefings in bioinformatics
Accurate sample classification using transcriptomics data is crucial for advancing personalized medicine. Achieving this goal necessitates determining a suitable sample size that ensures adequate classification accuracy without undue resource allocat...

Estimating Average Treatment Effects With Support Vector Machines.

Statistics in medicine
Support vector machine (SVM) is one of the most popular classification algorithms in the machine learning literature. We demonstrate that SVM can be used to balance covariates and estimate average causal effects under the unconfoundedness assumption....

Innovative statistical approaches: the use of neural networks reduces the sample size in the splenectomy-MCAO mouse model.

Croatian medical journal
AIM: To compare the effectiveness of artificial neural network (ANN) and traditional statistical analysis on identical data sets within the splenectomy-middle carotid artery occlusion (MCAO) mouse model.

Adaptive selection of the optimal strategy to improve precision and power in randomized trials.

Biometrics
Benkeser et al. demonstrate how adjustment for baseline covariates in randomized trials can meaningfully improve precision for a variety of outcome types. Their findings build on a long history, starting in 1932 with R.A. Fisher and including more re...

Post Hoc Sample Size Estimation for Deep Learning Architectures for ECG-Classification.

Studies in health technology and informatics
Deep Learning architectures for time series require a large number of training samples, however traditional sample size estimation for sufficient model performance is not applicable for machine learning, especially in the field of electrocardiograms ...

[Effects of sample size and data augmentation on U-Net-based automatic segmentation of various organs].

Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics

An analysis of the effects of limited training data in distributed learning scenarios for brain age prediction.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Distributed learning avoids problems associated with central data collection by training models locally at each site. This can be achieved by federated learning (FL) aggregating multiple models that were trained in parallel or training a s...

A Comparative Study on the Potential of Unsupervised Deep Learning-based Feature Selection in Radiomics.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
In Radiomics, deep learning-based systems for medical image analysis play an increasing role. However, due to the better explainability, feature-based systems are still preferred, especially by physicians. Often, high-dimensional data and low sample ...

Machine Learning Model Validation for Early Stage Studies with Small Sample Sizes.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
In early stage biomedical studies, small datasets are common due to the high cost and difficulty of sample collection with human subjects. This complicates the validation of machine learning models, which are best suited for large datasets. In this w...

Synthetic observations from deep generative models and binary omics data with limited sample size.

Briefings in bioinformatics
Deep generative models can be trained to represent the joint distribution of data, such as measurements of single nucleotide polymorphisms (SNPs) from several individuals. Subsequently, synthetic observations are obtained by drawing from this distrib...