AIMC Topic: SARS-CoV-2
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Large-Scale Deep Learning-Enabled Infodemiological Analysis of Substance Use Patterns on Social Media: Insights From the COVID-19 Pandemic.
JMIR infodemiology
Apr 17, 2025
BACKGROUND: The COVID-19 pandemic intensified the challenges associated with mental health and substance use (SU), with societal and economic upheavals leading to heightened stress and increased reliance on drugs as a coping mechanism. Centers for Di...
Combining machine learning and dynamic system techniques to early detection of respiratory outbreaks in routinely collected primary healthcare records.
BMC medical research methodology
Apr 16, 2025
BACKGROUND: Methods that enable early outbreak detection represent powerful tools in epidemiological surveillance, allowing adequate planning and timely response to disease surges. Syndromic surveillance data collected from primary healthcare encount...
Changes in recreational drug use, reasons for those changes and their consequence during and after the COVID-19 pandemic in the UK.
Comprehensive psychiatry
Apr 15, 2025
Changes in drug use in the general population during the COVID-19 pandemic and their long-term consequences are not well understood. We employed natural language processing and machine learning to analyse a large dataset of self-reported rates of and...
Machine Learning Interpretation of Optical Spectroscopy Using Peak-Sensitive Logistic Regression.
ACS nano
Apr 15, 2025
Optical spectroscopy, a noninvasive molecular sensing technique, offers valuable insights into material characterization, molecule identification, and biosample analysis. Despite the informativeness of high-dimensional optical spectra, their interpre...
Unraveling relevant cross-waves pattern drifts in patient-hospital risk factors among hospitalized COVID-19 patients using explainable machine learning methods.
BMC infectious diseases
Apr 15, 2025
BACKGROUND: Several studies explored factors related to adverse clinical outcomes among COVID-19 patients but lacked analysis of the impact of the temporal data shifts on the strength of association between different predictors and adverse outcomes. ...
Remdesivir associated with reduced mortality in hospitalized COVID-19 patients: treatment effectiveness using real-world data and natural language processing.
BMC infectious diseases
Apr 12, 2025
BACKGROUND: Remdesivir (RDV) was the first antiviral approved for mild-to-moderate COVID-19 and for those patients at risk for progression to severe disease after clinical trials supported its association with improved outcomes. Real-world evidence (...
Oxidative Stress Markers and Prediction of Severity With a Machine Learning Approach in Hospitalized Patients With COVID-19 and Severe Lung Disease: Observational, Retrospective, Single-Center Feasibility Study.
JMIR formative research
Apr 11, 2025
BACKGROUND: Serious pulmonary pathologies of infectious, viral, or bacterial origin are accompanied by inflammation and an increase in oxidative stress (OS). In these situations, biological measurements of OS are technically difficult to obtain, and ...
Analyzing the impact of COVID-19 on seasonal infectious disease outbreak detection using hybrid SARIMAX-LSTM model.
Journal of infection and public health
Apr 10, 2025
BACKGROUND: This study estimates the incidence of seasonal infectious diseases, including influenza, norovirus, severe fever with thrombocytopenia syndrome (SFTS), and tsutsugamushi disease, in the Republic of Korea from 2005 to 2023. It also examine...
Enhancing the understandings on SARS-CoV-2 main protease (M) mutants from molecular dynamics and machine learning.
International journal of biological macromolecules
Apr 10, 2025
While star drugs like Paxlovid have shown remarkable performance in combating SARS-CoV-2, we still face serious challenges such as viral mutants and resistance. In this study, we employ a computational framework combining molecular dynamics (MD) simu...
Predicting viral host codon fitness and path shifting through tree-based learning on codon usage biases and genomic characteristics.
Scientific reports
Apr 10, 2025
Viral codon fitness (VCF) of the host and the VCF shifting has seldom been studied under quantitative measurements, although they could be concepts vital to understand pathogen epidemiology. This study demonstrates that the relative synonymous codon ...
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