AIMC Topic: Sepsis-Associated Encephalopathy

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Integrated multi omics and machine learning reveal mitochondrial immunometabolic networks in sepsis associated encephalopathy.

Scientific reports
Sepsis-associated encephalopathy (SAE) is a major complication in intensive care units, characterized by diffuse brain dysfunction due to systemic inflammation. Despite advances in critical care medicine, SAE remains a key factor in poor patient outc...

Early prediction of sepsis associated encephalopathy in elderly ICU patients using machine learning models: a retrospective study based on the MIMIC-IV database.

Frontiers in cellular and infection microbiology
BACKGROUND: Sepsis associated encephalopathy (SAE) is prevalent among elderly patients in the ICU and significantly affects patient prognosis. Due to the symptom similarity with other neurological disorders and the absence of specific biomarkers, ear...

Identification of sepsis-associated encephalopathy biomarkers through machine learning and bioinformatics approaches.

Scientific reports
Sepsis-associated encephalopathy (SAE) is common in septic patients, characterized by acute and long-term cognitive impairment, and is associated with higher mortality. This study aimed to identify SAE-related biomarkers and evaluate their diagnostic...