Nucleic acids exhibit a repertoire of conformational preference depending on the sequence and environment. Circular dichroism (CD) is an essential and valuable tool for monitoring such secondary structural conformations of nucleic acids. Nonetheless,...
Advances in artificial intelligence research allow us to build fairly sophisticated agents: robots and computer programs capable of acting and deciding on their own (in some sense). These systems raise questions about who is responsible when somethin...
Cell wall lytic enzymes play key roles in biochemical, morphological, genetic research and industry fields. To save time and labor costs， bioinformatic methods are usually adopted to narrow the scope of in vitro experimentation. In this paper, we est...
Computer methods and programs in biomedicine
Aug 18, 2020
BACKGROUND AND OBJECTIVE: Cardiotocography (CTG) is the most employed methodology to monitor the foetus in the prenatal phase. Since the evaluation of CTG is often visual, and hence qualitative and too subjective, some automated methods have been int...
Bone metastasis is one of the most frequent diseases in prostate cancer; scintigraphy imaging is particularly important for the clinical diagnosis of bone metastasis. Up to date, minimal research has been conducted regarding the application of machin...
Drug repurposing, identifying novel indications for drugs, bypasses common drug development pitfalls to ultimately deliver therapies to patients faster. However, most repurposing discoveries have been led by anecdotal observations (e.g. Viagra) or ex...
Journal of bioinformatics and computational biology
Aug 6, 2020
The secondary and tertiary structure of a protein has a primary role in determining its function. Even though many folding prediction algorithms have been developed in the past decades - mainly based on the assumption that folding instructions are en...
With the high prevalence of breast cancer, it is urgent to find out the intrinsic difference between various subtypes, so as to infer the underlying mechanisms. Given the available multi-omics data, their proper integration can improve the accuracy o...
OBJECTIVE: The study aims to assess the impact of radiomics in the clinical practice of breast ultrasound, to determine which lesions are undetermined by the software, and to discuss the future of the radiologist's role.
Neural networks : the official journal of the International Neural Network Society
Jul 29, 2020
Steganography is the art of embedding a confidential message within a host message. Modern steganography is focused on widely used multimedia file formats, such as images, video files, and Internet protocols. Recently, cyber attackers have begun to i...
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