Accurate and sensitive pathogen detection is critical for the prevention and control of respiratory viral infections, which pose significant threats to global health, particularly for vulnerable populations such as children, the elderly, and immunoco...
A comprehensive understanding of protein corona (PC) composition is critical for engineering nanoparticles (NPs) with optimal safety and therapeutic performance, because the PC governs NP pharmacokinetics, biodistribution, and cellular interactions. ...
International journal of pharmaceutics
Sep 28, 2025
Dry powder inhalers (DPIs) are widely used for pulmonary drug delivery, and their aerodynamic performance is highly dependent on particle surface morphology. This paper presents a machine learning-based framework to quantitatively predict DPI aerodyn...
Surface-enhanced Raman spectroscopy (SERS) has shown potential for early disease diagnosis via urinary metabolomics, but still faces challenges in achieving stable hot spots and processing complex clinical data. In this study, the preparation of chir...
Journal of colloid and interface science
Sep 6, 2025
Developing high-performance wearable flexible sensors that can adapt well to complex environments has become a hotspot. Herein, a polyvinyl alcohol based composite hydrogel sensor with high mechanical strength, desirable frost/swelling resistance, an...
In this study, an adaptive force-position-speed collaborative process planning framework for robot polishing was proposed to improve the stability of the robot polishing process. The material removal model based on Preston's theory was studied, and t...
Journal of chemical information and modeling
Aug 12, 2025
We propose an active learning (AL) framework to develop classical force fields (FFs) that accurately model the potential energy surfaces (PES) of gas/solid atomic-scale complexes. A central challenge is integrating AL with flexible, computationally e...
Surface-enhanced Raman scattering (SERS) has demonstrated remarkable potential for molecular detection due to its specificity. However, detecting fluorescent vitamin B molecules remains challenging due to fluorescence interference and weak Raman cros...
This study introduces a novel approach to dengue diagnostics by leveraging surface-enhanced Raman spectroscopy (SERS) coupled to machine learning. This method addresses the critical need for rapid and accurate identification of dengue virus (DENV) in...
As nanomaterials increasingly interact with complex biological environments, understanding and designing their interfacial layers is critical for enabling functional and responsive behaviors. The protein corona, a spontaneously formed biomolecular la...
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