AIMC Topic: Synapses

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Synaptic damage underlies EEG abnormalities in postanoxic encephalopathy: A computational study.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: In postanoxic coma, EEG patterns indicate the severity of encephalopathy and typically evolve in time. We aim to improve the understanding of pathophysiological mechanisms underlying these EEG abnormalities.

Decision-making neural circuits mediating social behaviors : An attractor network model.

Journal of computational neuroscience
We propose a mathematical model of a continuous attractor network that controls social behaviors. The model is examined with bifurcation analysis and computer simulations. The results show that the model exhibits stable steady states and thresholds f...

Neuromorphic device architectures with global connectivity through electrolyte gating.

Nature communications
Information processing in the brain takes place in a network of neurons that are connected with each other by an immense number of synapses. At the same time, neurons are immersed in a common electrochemical environment, and global parameters such as...

An online supervised learning method based on gradient descent for spiking neurons.

Neural networks : the official journal of the International Neural Network Society
The purpose of supervised learning with temporal encoding for spiking neurons is to make the neurons emit a specific spike train encoded by precise firing times of spikes. The gradient-descent-based (GDB) learning methods are widely used and verified...

Avoiding Catastrophic Forgetting.

Trends in cognitive sciences
Humans regularly perform new learning without losing memory for previous information, but neural network models suffer from the phenomenon of catastrophic forgetting in which new learning impairs prior function. A recent article presents an algorithm...

Mimicking Neurotransmitter Release in Chemical Synapses via Hysteresis Engineering in MoS Transistors.

ACS nano
Neurotransmitter release in chemical synapses is fundamental to diverse brain functions such as motor action, learning, cognition, emotion, perception, and consciousness. Moreover, improper functioning or abnormal release of neurotransmitter is assoc...

Learning by stimulation avoidance: A principle to control spiking neural networks dynamics.

PloS one
Learning based on networks of real neurons, and learning based on biologically inspired models of neural networks, have yet to find general learning rules leading to widespread applications. In this paper, we argue for the existence of a principle al...

Dendritic trafficking faces physiologically critical speed-precision tradeoffs.

eLife
Nervous system function requires intracellular transport of channels, receptors, mRNAs, and other cargo throughout complex neuronal morphologies. Local signals such as synaptic input can regulate cargo trafficking, motivating the leading conceptual m...

Synaptic Correlates of Working Memory Capacity.

Neuron
Psychological studies indicate that human ability to keep information in readily accessible working memory is limited to four items for most people. This extremely low capacity severely limits execution of many cognitive tasks, but its neuronal under...

A Hybrid CMOS-Memristor Neuromorphic Synapse.

IEEE transactions on biomedical circuits and systems
Although data processing technology continues to advance at an astonishing rate, computers with brain-like processing capabilities still elude us. It is envisioned that such computers may be achieved by the fusion of neuroscience and nano-electronics...