AIMC Topic: Tissue Engineering
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3D Bioprinting and Artificial Intelligence-Assisted Biofabrication of Personalized Oral Soft Tissue Constructs.
Advanced healthcare materials
Dec 17, 2024
Regeneration of oral soft tissue defects, including mucogingival defects associated with the recession or loss of gingival and/or mucosal tissues around teeth and implants, is crucial for restoring oral tissue form, function, and health. This study p...
Progress of AI assisted synthesis of polysaccharides-based hydrogel and their applications in biomedical field.
International journal of biological macromolecules
Dec 10, 2024
Polymeric hydrogels, characterized by their highly hydrophilic three-dimensional network structures, boast exceptional physical and chemical properties alongside high biocompatibility and biodegradability. These attributes make them indispensable in ...
A programmable, open-source robot that scratches cultured tissues to investigate cell migration, healing, and tissue sculpting.
Cell reports methods
Dec 9, 2024
Despite the widespread popularity of the "scratch assay," where a pipette is dragged manually through cultured tissue to create a gap to study cell migration and healing, it carries significant drawbacks. Its heavy reliance on manual technique can co...
3D Printing of a Biomimetic Myotendinous Junction Assisted by Artificial Intelligence.
Biomaterials science
Nov 19, 2024
The myotendinous junction (MTJ) facilitates force transmission between muscle and tendon to produce joint movement. The complex microarchitecture and regional mechanical heterogeneity of the myotendinous junction pose major challenges in creating thi...
AI for biofabrication.
Biofabrication
Nov 4, 2024
Biofabrication is an advanced technology that holds great promise for constructing highly biomimeticthree-dimensional human organs. Such technology would help address the issues of immune rejection and organ donor shortage in organ transplantation, a...
AI-Based solutions for current challenges in regenerative medicine.
European journal of pharmacology
Oct 24, 2024
The emergence of Artificial Intelligence (AI) and its usage in regenerative medicine represents a significant opportunity that holds the promise of tackling critical challenges and improving therapeutic outcomes. This article examines the ways in whi...
Enhanced drug classification using machine learning with multiplexed cardiac contractility assays.
Pharmacological research
Oct 11, 2024
Cardiac screening of newly discovered drugs remains a longstanding challenge for the pharmaceutical industry. While therapeutic efficacy and cardiotoxicity are evaluated through preclinical biochemical and animal testing, 90 % of lead compounds fail ...
Biohybrid Micro/Nanorobots: Pioneering the Next Generation of Medical Technology.
Advanced healthcare materials
Oct 7, 2024
Biohybrid micro/nanorobots hold a great potential for advancing biomedical research. These tiny structures, designed to mimic biological organisms, offer a promising method for targeted drug delivery, tissue engineering, biosensing/imaging, and cance...
ReBiA-Robotic Enabled Biological Automation: 3D Epithelial Tissue Production.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sep 26, 2024
The Food and Drug Administration's recent decision to eliminate mandatory animal testing for drug approval marks a significant shift to alternative methods. Similarly, the European Parliament is advocating for a faster transition, reflecting public p...
Prediction of directional solidification in freeze casting of biomaterial scaffolds using physics-informed neural networks.
Biomedical physics & engineering express
Sep 20, 2024
Freeze casting, a manufacturing technique widely applied in biomedical fields for fabricating biomaterial scaffolds, poses challenges for predicting directional solidification due to its highly nonlinear behavior and complex interplay of process para...
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