Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Jan 14, 2026
The application of machine learning (ML) and artificial intelligence (AI) algorithms in medical imaging is an emerging area of interest, particularly in the context of clinical decision-making. Here, we report on the overall performance (i.e., sensit...
Journal of nuclear medicine technology
Dec 3, 2025
The aim of the study was to validate a new method for semiautomatic subtraction of [Tc]Tc-sestamibi and [Tc]NaTcO SPECT 3-dimensional datasets using principal component analysis (PCA) against the results of parathyroid surgery and to compare its perf...
BACKGROUND: Parkinson's disease is a movement disorder featuring motor symptoms and cognitive decline, which can manifest as mild cognitive impairment. The incidence of mild cognitive impairment increases with disease progression, and Parkinson's dis...
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by a wide spectrum of motor and non-motor symptoms, often leading to delayed or inaccurate diagnosis. Conventional diagnostic methods frequently suffer from limited se...
. In single-photon emission computed tomography (SPECT) image reconstruction, limited-angle conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected proje...
SPECT is a widely used imaging modality in nuclear medicine which provides essential functional insights into cardiovascular, neurological, and oncological diseases. However, SPECT imaging suffers from limited quantitative accuracy due to low spatial...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Apr 1, 2025
We previously demonstrated that a deep learning (DL) model of myocardial perfusion SPECT imaging improved accuracy for detection of obstructive coronary artery disease (CAD). We aimed to improve the clinical translatability of this artificial intelli...
OBJECTIVE: To provide fully automatic scanner-independent 5-level categorization of the [I]FP-CIT uptake in striatal subregions in dopamine transporter SPECT.
European journal of nuclear medicine and molecular imaging
Feb 20, 2025
BACKGROUND: Myocardial perfusion imaging (MPI) using single-photon emission computed tomography (SPECT) is a well-established modality for noninvasive diagnostic assessment of coronary artery disease (CAD). However, the time-consuming and experience-...
OBJECTIVE: Functional imaging using the dopamine transporter (DAT) as a biomarker has proven effective in assessing dopaminergic neuron degeneration in the striatum. In assessing the neuron degeneration, visual and semiquantitative methods are used t...
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