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Artificial intelligence in clinical and translational science: Successes, challenges and opportunities.

Clinical and translational science
Artificial intelligence (AI) is transforming many domains, including finance, agriculture, defense, and biomedicine. In this paper, we focus on the role of AI in clinical and translational research (CTR), including preclinical research (T1), clinical...

Low-value care and excess out-of-pocket expenditure among older adults with incident cancer - A machine learning approach.

Journal of cancer policy
OBJECTIVE: To evaluate the association of low-value care with excess out-of-pocket expenditure among older adults diagnosed with incident breast, prostate, colorectal cancers, and Non-Hodgkin's Lymphoma.

Association of Individual and Community Factors With Hepatitis C Infections Among Pregnant People and Newborns.

JAMA health forum
IMPORTANCE: The opioid crisis has increasingly affected pregnant people and infants. Hepatitis C virus (HCV) infections, a known complication of opioid use, grew in parallel with opioid-related complications; however, the literature informing individ...

Rilpivirine plus cobicistat-boosted darunavir as alternative to standard three-drug therapy in HIV-infected, virologically suppressed subjects: Final results of the PROBE 2 trial.

Antiviral therapy
BACKGROUND: Primary analysis at 24 weeks showed that switching to rilpivirine plus darunavir/cobicistat was non-inferior to continuing a standard three-drug antiretroviral regimen in virologically suppressed people with HIV. We present efficacy and s...

Phenotype Discovery and Geographic Disparities of Late-Stage Breast Cancer Diagnosis across U.S. Counties: A Machine Learning Approach.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
BACKGROUND: Disparities in the stage at diagnosis for breast cancer have been independently associated with various contextual characteristics. Understanding which combinations of these characteristics indicate highest risk, and where they are locate...

What influences attitudes about artificial intelligence adoption: Evidence from U.S. local officials.

PloS one
Rapid advances in machine learning and related techniques have increased optimism about self-driving cars, autonomous surgery, and other uses of artificial intelligence (AI). But adoption of these technologies is not simply a matter of breakthroughs ...

FROM NASA TO HEALTHCARE: REAL-TIME DATA ANALYTICS (MISSION CONTROL) IS RESHAPING HEALTHCARE SERVICES.

Perspectives in health information management
This is a case study of the implementation of a data and analytics-enabled Mission Control at one of the largest healthcare service providers in the state of Washington. Using data analytics and artificial intelligence, CHI-Franciscan (one of the lar...

Deep Learning for Identification of Alcohol-Related Content on Social Media (Reddit and Twitter): Exploratory Analysis of Alcohol-Related Outcomes.

Journal of medical Internet research
BACKGROUND: Many social media studies have explored the ability of thematic structures, such as hashtags and subreddits, to identify information related to a wide variety of mental health disorders. However, studies and models trained on specific the...

Deep Learning Computer-aided Polyp Detection Reduces Adenoma Miss Rate: A United States Multi-center Randomized Tandem Colonoscopy Study (CADeT-CS Trial).

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
BACKGROUND & AIMS: Artificial intelligence-based computer-aided polyp detection (CADe) systems are intended to address the issue of missed polyps during colonoscopy. The effect of CADe during screening and surveillance colonoscopy has not previously ...

Application of a time-series deep learning model to predict cardiac dysrhythmias in electronic health records.

PloS one
BACKGROUND: Cardiac dysrhythmias (CD) affect millions of Americans in the United States (US), and are associated with considerable morbidity and mortality. New strategies to combat this growing problem are urgently needed.