AIMC Topic: Uterine Cervical Neoplasms

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MVT-Net: A novel cervical tumour segmentation using multi-view feature transfer learning.

PloS one
Cervical cancer is one of the most aggressive malignant tumours of the reproductive system, posing a significant global threat to women's health. Accurately segmenting cervical tumours in MR images remains a challenging task due to the complex charac...

Quantitative and automatic plan-of-the-day assessment to facilitate adaptive radiotherapy in cervical cancer.

Physics in medicine and biology
To facilitate implementation of plan-of-the-day (POTD) selection for treating locally advanced cervical cancer (LACC), we developed a POTD assessment tool for CBCT-guided radiotherapy (RT). A female pelvis segmentation model (U-Seg3) is combined with...

Deep learning-based automatic dose optimization for brachytherapy.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
PURPOSE: The purpose of this study is to determine the best dose processing method for deep learning-based dose prediction in brachytherapy (BT), as well as to investigate the feasibility of using the inverse dose optimization algorithm to improve tr...

Split DNA Tetrahedron-Mediated Spatiotemporal-Hierarchy CRISPR Cascade Integrated with Au@Pt Nanolabels and Artificial Intelligence for a Cervical Cancer MicroRNA Bioassay.

ACS nano
The screening and monitoring of microRNAs as cancer molecular biomarkers is clinically significant, but traditional methods lack sufficient sensitivity, accuracy, and convenience. The CRISPR-colorimetric lateral flow assay (CLFA) integration offers a...

Challenges and Opportunities for Global Cervical Cancer Elimination: How Can We Build a Model for Other Cancers?

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
Cervical cancer remains a leading cause of cancer-related death among women globally, despite the availability of effective prevention through human papillomavirus (HPV) vaccination and HPV-based screening. This review explores the state-of-the-art t...

Deep learning-based applicator selection between Syed and T&O in high-dose-rate brachytherapy for locally advanced cervical cancer: a retrospective study.

Physics in medicine and biology
High-dose-rate (HDR) brachytherapy is integral to the standard-of-care for locally advanced cervical cancer (LACC). Currently, selection of brachytherapy applicators relies on physician's clinical experience, which can lead to variability in treatmen...

Molecular detection of hrHPV-induced high-grade squamous intraepithelial lesions of the cervix through a targeted RNA next generation sequencing assay.

Molecular medicine (Cambridge, Mass.)
BACKGROUND: Cervical cancer screening programs are increasingly relying on sensitive molecular approaches as primary tests to detect high-risk human papillomaviruses (hrHPV), the causative agents of cervix cancer. Although hrHPV infection is a pre-re...

Study on the relationship between vaginal dose and radiation-induced vaginal injury following cervical cancer radiotherapy, and model development.

Frontiers in public health
OBJECTIVE: This study investigates the relationship between vaginal radiation dose and radiation-induced vaginal injury in cervical cancer patients, with the aim of developing a risk prediction model to support personalized treatment strategies.

Exploring potential methylation markers for ovarian cancer from cervical scraping samples.

Human genomics
BACKGROUND: Ovarian cancer has the highest mortality rate among gynecological cancers, making early detection crucial, as the five-year survival rate drops from 92% with early-stage diagnosis compared to 31% with late-stage diagnosis. Current diagnos...

Fully Automated Online Adaptive Radiation Therapy Decision-Making for Cervical Cancer Using Artificial Intelligence.

International journal of radiation oncology, biology, physics
BACKGROUND: Interfraction variations during radiation therapy pose a challenge for patients with cervical cancer, highlighting the benefits of online adaptive radiation therapy (oART). However, adaptation decisions rely on subjective image reviews by...