AIMC Topic: Vancomycin
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Prediction of Vancomycin-Associated Nephrotoxicity Based on the Area under the Concentration-Time Curve of Vancomycin: A Machine Learning Analysis.
Biological & pharmaceutical bulletin
Jan 1, 2024
Several machine learning models have been proposed to predict vancomycin (VCM)-associated nephrotoxicity; however, they have notable limitations. Specifically, they do not use the area under the concentration-time curve (AUC) as recommended in the la...
Data-Driven Clinical Pharmacy Research: Utilizing Machine Learning and Medical Big Data.
Biological & pharmaceutical bulletin
Jan 1, 2024
To conduct clinical pharmacy research, we often face the limitations of conventional statistical methods and single-center observational study. To overcome these issues, we have conducted data-driven research using machine learning methods and medica...
STABILITY-INDICATING HPLC METHOD FOR DETERMINATION OF VANCOMYCIN HYDROCHLORIDE IN THE PHARMACEUTICAL DOSAGE FORMS.
Acta poloniae pharmaceutica
Jan 1, 2017
A simple, rapid and selective RP-HPLC method was developed for the determination of vancomycin hydrochloride. The separation was achieved using a Capital C8-Optimal column (250 x 4.6 mm i.d., 5 μm particle size) with a mobile phase composed of buffer...
Currently used dosage regimens of vancomycin fail to achieve therapeutic levels in approximately 40% of intensive care unit patients.
Revista Brasileira de terapia intensiva
Jan 1, 2016
OBJECTIVE:: This study aimed to assess whether currently used dosages of vancomycin for treatment of serious gram-positive bacterial infections in intensive care unit patients provided initial therapeutic vancomycin trough levels and to examine possi...
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