AIMC Topic: Viscosity

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Machine Learning Models for Predicting Monoclonal Antibody Biophysical Properties from Molecular Dynamics Simulations and Deep Learning-Based Surface Descriptors.

Molecular pharmaceutics Nov 28, 2024
Monoclonal antibodies (mAbs) have found extensive applications and development in treating various diseases. From the pharmaceutical industry's perspective, the journey from the design and development of mAbs to clinical testing and large-scale produ...
Humans Machine Learning Molecular Dynamics Simulation Solubility Viscosity Deep Learning Antibodies, Monoclonal
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Neural Network-Enabled Multiparametric Impedance Signal Templating for High throughput Single-Cell Deformability Cytometry Under Viscoelastic Extensional Flows.

Small (Weinheim an der Bergstrasse, Germany) Oct 22, 2024
Cellular biophysical metrics exhibit systematic alterations during processes, such as metastasis and immune cell activation, which can be used to identify and separate live cell subpopulations for targeting drug screening. Image-based biophysical cyt...
Elasticity Viscosity Humans Neural Networks, Computer Flow Cytometry Electric Impedance Single-Cell Analysis
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Rheological modelling of apple puree based on machine learning combined Monte Carlo simulation: Insight into the fundamental light- particle structure interaction processes.

Food chemistry Oct 10, 2024
In this work, apple purees from different particle concentration and verifying in size were reconstituted to investigate their impacts on rheological behaviors, optical properties and light interaction at 900-1650 nm. The optical scattering of differ...
Machine Learning Particle Size Viscosity Light Fruit Monte Carlo Method Rheology Malus
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Encoding spatiotemporal asymmetry in artificial cilia with a ctenophore-inspired soft-robotic platform.

Bioinspiration & biomimetics Sep 20, 2024
A remarkable variety of organisms use metachronal coordination (i.e. numerous neighboring appendages beating sequentially with a fixed phase lag) to swim or pump fluid. This coordination strategy is used by microorganisms to break symmetry at small s...
Viscosity Biomimetic Materials Hydrodynamics Rheology Swimming Ctenophora Silicone Elastomers Cilia Biomechanical Phenomena Animals Equipment Design Biomimetics Robotics
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Constraint based Bayesian optimization of bioink precursor: a machine learning framework.

Biofabrication Aug 28, 2024
Current research practice for optimizing bioink involves exhaustive experimentation with multi-material composition for determining the printability, shape fidelity and biocompatibility. Predicting bioink properties can be beneficial to the research ...
Viscosity Ink Bayes Theorem Bioprinting Animals Machine Learning Mice
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Artificial intelligence-based prediction of the rheological properties of hydrocolloids for plant-based meat analogues.

Journal of the science of food and agriculture Feb 8, 2024
BACKGROUND: Methylcellulose has been applied as a primary binding agent to control the quality attributes of plant-based meat analogues. H owever, a great deal of effort has been made to search for hydrocolloids to replace methylcellulose because of ...
Artificial Intelligence Colloids Meat Substitutes Meat Products Rheology Viscosity Machine Learning Algorithms
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Self-assembled pH-stable gellan/κ-carrageenan bigel: Rheological studies and viscosity prediction by neural network.

International journal of biological macromolecules Mar 16, 2023
The current study focused on analysing and predicting the effect of physicochemical parameters on the rheological properties of the novel polysaccharide-based bigel. This is the first study to report a bigel fabricated entirely from polysaccharides a...
Gels Polysaccharides, Bacterial Carrageenan Hydrogen-Ion Concentration Viscosity Rheology Neural Networks, Computer
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Low-data interpretable deep learning prediction of antibody viscosity using a biophysically meaningful representation.

Scientific reports Feb 20, 2023
Deep learning, aided by the availability of big data sets, has led to substantial advances across many disciplines. However, many scientific problems of practical interest lack sufficiently large datasets amenable to deep learning. Prediction of anti...
Immunoglobulin Variable Region Big Data Antibodies Viscosity Deep Learning
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A novel soft robotic pediatric in vitro swallowing device to gain insights into the swallowability of mini-tablets.

International journal of pharmaceutics Nov 6, 2022
Soft robotics could help providing a better understanding of the mechanisms underpinning the swallowability of solid oral dosage forms (SODF), especially by vulnerable populations such as the elderly or children. In this study a novel soft robotic in...
Robotics Tablets Deglutition Excipients Viscosity Child, Preschool Child Humans Aged
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Viscoelasticity assessment of tumoral skin with the use of a novel contact-free palpation methodology based upon surface waves.

Scientific reports Nov 4, 2022
The ensuing pilot investigation sheds new light on characterizing tumoral and non-tumoral human skin mechanical properties that will not only assist the dermatologist's diagnosis but also could constitute the creation of an Artificial Intelligence da...
Skin Neoplasms Skin Viscosity Humans Artificial Intelligence Palpation
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