AIMC Topic: Vocabulary, Controlled

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Learning disease relationships from clinical drug trials.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Our objective is to test the limits of the assumption that better learning from data in medicine requires more granular data. We hypothesize that clinical trial metadata contains latent scientific, clinical, and regulatory expert knowledge...

Learning statistical models of phenotypes using noisy labeled training data.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Traditionally, patient groups with a phenotype are selected through rule-based definitions whose creation and validation are time-consuming. Machine learning approaches to electronic phenotyping are limited by the paucity of labeled traini...

Developing a web-based SKOS editor.

Journal of biomedical semantics
BACKGROUND: The Simple Knowledge Organization System (SKOS) was introduced to the wider research community by a 2005 World Wide Web Consortium (W3C) working draft, and further developed and refined in a 2009 W3C recommendation. Since then, SKOS has b...

Ontology Alignment Repair through Modularization and Confidence-Based Heuristics.

PloS one
Ontology Matching aims at identifying a set of semantic correspondences, called an alignment, between related ontologies. In recent years, there has been a growing interest in efficient and effective matching methods for large ontologies. However, al...

Biological Model Development as an Opportunity to Provide Content Auditing for the Foundational Model of Anatomy Ontology.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Constructing a biological model using an established ontology provides a unique opportunity to perform content auditing on the ontology. We built a Markov chain model to study tumor metastasis in the regional lymphatics of patients with head and neck...

Automatic Extraction and Post-coordination of Spatial Relations in Consumer Language.

AMIA ... Annual Symposium proceedings. AMIA Symposium
To incorporate ontological concepts in natural language processing (NLP) it is often necessary to combine simple concepts into complex concepts (post-coordination). This is especially true in consumer language, where a more limited vocabulary forces ...

Drug-drug Interaction Discovery Using Abstraction Networks for "National Drug File - Reference Terminology" Chemical Ingredients.

AMIA ... Annual Symposium proceedings. AMIA Symposium
The National Drug File - Reference Terminology (NDF-RT) is a large and complex drug terminology. NDF-RT provides important information about clinical drugs, e.g., their chemical ingredients, mechanisms of action, dosage form and physiological effects...

Combining Search, Social Media, and Traditional Data Sources to Improve Influenza Surveillance.

PLoS computational biology
We present a machine learning-based methodology capable of providing real-time ("nowcast") and forecast estimates of influenza activity in the US by leveraging data from multiple data sources including: Google searches, Twitter microblogs, nearly rea...