AIMC Topic: Warfarin

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Revisiting Warfarin Dosing Using Machine Learning Techniques.

Computational and mathematical methods in medicine Jun 4, 2015
Determining the appropriate dosage of warfarin is an important yet challenging task. Several prediction models have been proposed to estimate a therapeutic dose for patients. The models are either clinical models which contain clinical and demographi...
Drug Administration Schedule False Positive Reactions Anticoagulants Warfarin Pharmacogenetics Genotype Dose-Response Relationship, Drug Regression Analysis Reproducibility of Results Male Databases, Factual Female Machine Learning Algorithms Humans
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[Application of an interpretable neural network framework based on the LASSO-proj algorithm for warfarin dose prediction].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi Dec 25, 2025
Warfarin, a classic oral anticoagulant, is characterized by a narrow therapeutic window and considerable interindividual variability in dosing requirements. This makes precise dose adjustment challenging in clinical practice and increases the risk of...
Algorithms Pharmacogenetics Warfarin Humans Neural Networks, Computer Genotype Drug Dosage Calculations Vitamin K Epoxide Reductases Anticoagulants
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Critical Appraisal on the Role of Warfarin in the Current Era.

The Journal of the Association of Physicians of India Oct 1, 2023
Warfarin has been the most extensively used oral anticoagulant (OAC) in medical settings for over 60 years. Its uses, potential adverse effects, and methods for reversing its effects have been firmly established, rendering it a routine medication in ...
Drug Monitoring Warfarin Humans International Normalized Ratio Anticoagulants
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Predictors of bleeding event among elderly patients with mechanical valve replacement using random forest model: A retrospective study.

Medicine May 14, 2021
Available classification tools and risk factors predicting bleeding events in elderly patients after mechanical valve replacement may not be suitable in Asian populations. Thus, we aimed to identify an accurate model for predicting bleeding in elderl...
Retrospective Studies Risk Factors Aged Humans Machine Learning Stroke Anticoagulants Myocardial Infarction Warfarin Heart Valve Prosthesis Implantation Risk Assessment Adrenal Cortex Hormones Hemorrhage Neoplasms
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Detecting Signals of Interactions Between Warfarin and Dietary Supplements in Electronic Health Records.

Studies in health technology and informatics Jan 1, 2017
Drug and supplement interactions (DSIs) have drawn widespread attention due to their potential to affect therapeutic response and adverse event risk. Electronic health records provide a valuable source where the signals of DSIs can be identified and ...
Herb-Drug Interactions Ginkgo biloba Humans Warfarin Drug Interactions Electronic Health Records Dietary Supplements
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Comparison of non-vitamin K antagonist oral anticoagulants and warfarin on clinical outcomes in atrial fibrillation patients with renal dysfunction.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Oct 1, 2015
AIMS: We aimed to compare the efficacy and safety between non-vitamin K antagonist oral anticoagulants (NOACs) and warfarin in atrial fibrillation (AF) patients according to renal dysfunction.
Comorbidity Treatment Outcome Causality Kidney Diseases Hemorrhage Male Thromboembolism Republic of Korea Prevalence Humans Female Atrial Fibrillation Aged Retrospective Studies Anticoagulants Risk Factors Vitamin K Survival Rate Warfarin
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