Nowadays, Y chromosome short tandem repeats (Y-STRs) are widely used in forensic medicine practice, which has great significance for ancestry tracing, male lineage evolution, and male paternal relatives. Rapidly mutating Y-STRs (RM Y-STRs) have been ... read more
BACKGROUND: Current clinical guidelines recommend gene expression profiling to guide treatment in early-stage breast cancer. PreciseBreast (PDxBR) is a digital prognostic tool that integrates artificial intelligence (AI)-derived features from hematox... read more
Multiple sclerosis (MS) affects 2.9 million people. Traditional classification of MS into distinct subtypes poorly reflects its pathobiology and has limited value for prognosticating disease evolution and treatment response, thereby hampering drug di... read more
Brain tumors have complex structures, and their shape, density, and size can vary widely. Consequently, their accurate classification, which involves identifying features that best describe the tumor data, is challenging. Using classical 2D texture f... read more
Luminescence imaging techniques assume a critical role in the evaluation of the durability and lifespan of solar cells. This study presents a novel empirical approach that capitalizes on simple machine learning-based linear regression (MLLR) to progn... read more
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Aug 20, 2025
Single-cell cis-regulatory relationships (CRRs) are essential for deciphering transcriptional regulation and understanding the pathogenic mechanisms of disease-associated non-coding variants. Existing computational methods struggle to accurately pred... read more
BACKGROUND: To identify risk factors for post-transplant mortality and develop a machine learning-integrated prognostic tool to optimise clinical decision-making in liver transplantation (LT) recipients. read more
BACKGROUND: Sarcopenia is associated with adverse outcomes in patients with end-stage heart failure. Muscle mass can be quantified via manual segmentation of computed tomography images, but this approach is time-consuming and subject to interobserver... read more
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