Latest AI and machine learning research in fda general for healthcare professionals.
Emerging evidence links reactive oxygen species modulator 1 (ROMO1), a key mitochondrial ROS regulator, to rheumatoid arthritis (RA) pathogenesis. However, its exact mechanism remains elusive given the conflicting evidence about its specific function. We used a four-level integrative framework combining multi-omics data and literature‑supported mechanistic inference. At the genetic level, Mendelia...
OBJECTIVE: This review presents Darwinian nanomedicine as an artificial intelligence (AI)-enabled drug delivery strategy that applies Darwinian evolutionary principles as a computational and engineering analogy. Rather than implying biological evolution of nanoparticles, the framework employs iterative cycles of variation, selection, adaptation, and computational inheritance to optimize nanopartic...
Small interfering RNA (siRNA) therapeutics have emerged as a transformative approach for sequence-specific gene silencing, offering the potential to t...
Drug-induced liver injury (DILI) is a complex and intractable disease because existing anti-oxidate therapies in clinic fail to modulate multiple path...
Machine learning (ML) is increasingly utilized in medical research. However, underrecognized methodological pitfalls can result in misleading conclusi...
BACKGROUND: Screening is important for early detection of cervical cancer in low- and middle-income countries. Visual inspection with acetic acid (VIA...
PURPOSE: Several clinical trial studies have shown correlations between certain physiological measurements and an ASD diagnosis. Such findings, howeve...
New Approach Methodologies (NAMs) represent a paradigm shift in drug development and regulatory science, offering human-relevant alternatives to tradi...
How domestication shapes brain evolution remains an open question. In this study, we integrated single-nucleus RNA sequencing (snRNA-seq), population ...
Soft robots excel at safe and adaptive interaction but are often constrained by limited load capacity and manipulation precision. Antagonistic soft ac...
Artificial intelligence (AI) is rapidly transforming histopathology, with applications ranging from workflow optimisation and quality assurance to tum...
The human cortex is complex and heterogeneous, undergoing extensive expansion during development1,2. Our prior study of neurogenesis, including radial...
BACKGROUND: Cleaning is the foundational step in medical device reprocessing; residual soil and biofilm can compromise disinfection and sterilization ...
Ambient artificial intelligence (AI) documentation tools, known as AI scribes, have entered psychiatric clinical practice, bundling at least three ope...
Prior authorization (PA) imposes substantial administrative burdens on clinicians, contributing to burnout, delayed care, and excess health care spend...
OBJECTIVE: White matter (WM), as the critical infrastructure for neural communication, is implicated in pediatric bipolar disorder (PBD) pathophysiolo...
Rheumatology faces sustained workforce strain, widening access gaps, and escalating administrative burden. Fellowship expansion and integration of adv...
Small interfering RNAs (siRNAs) are a clinically validated therapeutic modality with eight FDA-approved drugs, yet designing effective siRNAs remains ...
Nonlinear spiking neural P (NSNP) systems offer a biologically inspired framework for modeling nonlinear temporal dynamics via spike consumption and g...