Latest AI and machine learning research in inflammatory bowel disease for healthcare professionals.
Emerging evidence links reactive oxygen species modulator 1 (ROMO1), a key mitochondrial ROS regulator, to rheumatoid arthritis (RA) pathogenesis. However, its exact mechanism remains elusive given the conflicting evidence about its specific function. We used a four-level integrative framework combining multi-omics data and literature‑supported mechanistic inference. At the genetic level, Mendelia...
N- (1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q), a tire rubber antioxidant derivative, accumulates in air, soil, and water and has been found in urine, blood, and cerebrospinal fluid, posing significant health risks. Although 6PPD-Q exhibits intestinal toxicity, its role in inflammatory bowel disease (IBD) remains unclear. The objective of this study was to identify key molecu...
Machine learning (ML) is increasingly utilized in medical research. However, underrecognized methodological pitfalls can result in misleading conclusi...
BACKGROUND: Outcome prediction after Gamma Knife radiosurgery (GKRS) for pituitary adenomas remains guided by tumor anatomy, functional status, prior ...
Rheumatoid arthritis (RA) patients face increased cardiovascular (CV) risk, yet existing 10-year estimation tools often underperform. This study evalu...
BACKGROUND: Major depressive disorder exists along a continuum, from health through remission to active depression. Differentiating these states remai...
BACKGROUND: Optimal bowel preparation (BP) is crucial for a successful colonoscopy. Although multiple factors influence BP quality, including patient ...
Heart failure (HF) remains a major cause of morbidity, mortality, impaired quality of life and healthcare expenditure worldwide. The global burden of ...
The therapeutic landscape of haematological malignancies has evolved rapidly with the introduction of targeted therapies, immunotherapies, and cell-ba...
BACKGROUND: The management of severe asthma with biologics has become more complex involving multidisciplinary team meetings. Artificial intelligence ...
Butyrylcholinesterase (BChE) plays a key role in preserving appropriate cholinergic neurotransmission that is essentially altered in the brains of adv...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option for a significant proportion of patients with acute myel...
OBJECTIVE: To compare the ability of large language models (LLMs) and otolaryngologists to identify prognostic signals from brief clinical vignettes i...
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by inflammatory heterogeneity, epithelial hyperplasia, and tissue remodeling, with ...
Airway remodeling is increasingly recognized as a major determinant of asthma progression, fixed airflow limitation, and long-term morbidity, particul...
Despite substantial recent progress in inflammatory bowel disease (IBD) therapies, there remains a large proportion of patients who are non-responders...
Gene mutations and chromosome abnormalities are important components of prognostication in acute myeloid leukemia (AML). Here we assessed whether DNA ...
INTRODUCTION: We examined whether machine learning identified baseline variables that predicted two-year prevention and remission from anxiety, depres...
Sex steroid hormones, including estradiol (E2), estrone (E1), follicle-stimulating hormone (FSH), and luteinizing hormone (LH), have been implicated i...
Early identification of individuals at risk of developing psychosis enables timely intervention and better clinical outcomes. Current approach relies ...