Endocrinology

Diabetes

Latest AI and machine learning research in diabetes for healthcare professionals.

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Development of Insulin Bolus Calculators in Type 1 Diabetes Using a Framework Based on Real-World Data, Digital Twins and Machine Learning.

OBJECTIVE: Precise mealtime insulin bolus (MIB) dosing is essential in type 1 diabetes (T1D) to minimize glucose excursions from carbohydrate intake. Traditional MIB formulas, based on glucose concentration at mealtime, are suboptimal and do not exploit real-time data from continuous glucose monitoring (CGM). Existing methods that incorporate CGM data often rely on empirical rules or are developed...

Sep 1 2026 41447489

Development of a Prognostic Survival Risk Score for Lung Cancer Patients With Type 2 Diabetes Mellitus: A Territory-Wide Retrospective Cohort Study.

BACKGROUND: Lung cancer is a leading cause of cancer-related mortality, and its prognosis is often affected by comorbidities such as type 2 diabetes mellitus (T2DM). This study aimed to identify survival risk factors for lung cancer patients with T2DM, evaluate the predictive models, and develop a risk score system for survival prediction. STUDY DESIGN AND METHODS: We analyzed data from 5491 lung ...

Sep 1 2026 42655935
Artificial Intelligence-Estimated Intrapancreatic Fat and Its Relationship to Familial and Germline Pancreatic Cancer Risk.

BACKGROUND: Family history of pancreatic cancer (PC), pathogenic germline variants (PGVs), and increased intrapancreatic fat (IPF) are individually as...

Sep 1 2026 42666046
A Textile-Based, Battery-Free, Electrochromic Platform for Visual Epidermal Sweat Biosensing.

Noninvasive wearable sweat sensors are promising for personalized health management, yet their widespread adoption is hindered by complex multi-compon...

Aug 31 2026 42671390
Smartphone-Based Fundus Imaging in Global Eye Care: Closing the Gap.

Smartphone-based fundus imaging (SBFI) is an emerging approach with potential relevance for global ophthalmic care, including in low- and middle-incom...

Aug 31 2026 42674180
Identification of comorbidity-based clusters and mortality risk in hospitalised patients with diabetes mellitus in Karachi, Pakistan: a machine learning analysis.

BACKGROUND: Diabetes has reached epidemic proportions in Pakistan. This study applied machine learning (ML) techniques to identify comorbidity-based a...

Aug 31 2026 42674787
Retrospective population-based cohorts for assessing the performance of algorithmic diabetes classification and for quantifying the true burden of type 1, type 2 and LADA phenotypes in Quebec: a study protocol.

INTRODUCTION: Diabetes affects 537 million people worldwide, with type 2 diabetes (T2D) estimated to account for most cases. Type 1 diabetes (T1D), la...

Aug 31 2026 42674789
Bump2Baby & Me+ (B2B&Me+): Protocol for a multi-country, European hybrid type 3 implementation-effectiveness study to reduce the incidence of gestational diabetes mellitus and improve maternal and child health.

BACKGROUND: Gestational diabetes mellitus (GDM) affects 1-in-7 pregnancies globally and is associated with significant short- and long-term health con...

Aug 31 2026 42672070
Glucose-to-albumin ratio and mortality in ICU patients with acute pancreatitis.

OBJECTIVES: Acute pancreatitis (AP) carries a high mortality risk in ICU patients. The glucose-to-albumin ratio (GAR), reflecting metabolic stress and...

Aug 31 2026 42666811
Parkinson's Disease and Retinal Age Gap: A Cross-Sectional Analysis.

BACKGROUND: Deep-learning models are capable of predicting age from retinal scans and the difference between this and chronological age, retinal age g...

Aug 30 2026 42670076
Clinical and Metabolomic Panel for Noninvasive Screening of Biopsy-Confirmed MASH in Children and Adolescents.

BACKGROUND & AIMS: Noninvasive tests to identify pediatric metabolic dysfunction-associated steatohepatitis (MASH) remain a critical need. We aimed to...

Aug 30 2026 42669329
Non-Oncology Biomarkers in Precision Medicine: A Narrative Review.

Precision medicine has revolutionized oncology by leveraging biomarkers for individualized therapy selection, early diagnosis, and real-time disease m...

Aug 29 2026 42667586
Pooled two-cohort MRI body composition phenotyping with open-source deep learning.

BACKGROUND: Body mass index fails to capture variation in fat and muscle distribution that determines metabolic health and disease risk. MRI enables r...

Aug 29 2026 42668286
The Minimum Frequency of Well-Day Capillary Blood Ketone Testing Needed to Predict 1-Month Diabetic Ketoacidosis Risk in Type 1 Diabetes.

OBJECTIVE: Independent of clinical risk factors, performing well-day capillary ketone monitoring over a month predicts near-term diabetic ketoacidosis...

Aug 28 2026 42663523
Risks of Major Adverse Kidney Events in Non-Hispanic Black Patients with Diabetes or Hypertension: A real-world cohort study.

INTRODUCTION: Chronic kidney disease (CKD) disproportionately burdens non-Hispanic Black (NHB) patients who experience a three- to four-fold higher ri...

Aug 28 2026 42664178
Performance and label efficiency of traditional deep-learning models and a retina-specific foundation model for ocular and systemic disease detection: a retrospective comparative study.

BACKGROUND: RETFound, a self-supervised retina-specific foundation model, has shown potential in downstream tasks, but its performance in comparison w...

Aug 28 2026 42665469
Machine learning-based prediction model for predicting the impact of insulin resistance on the risk of ischemic cardiomyopathy.

BACKGROUND: The triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio and triglyceride glucose-body mass (TyG-BMI) index are reliable ...

Aug 28 2026 42665815
Distinct Conformational Switches Control WPD-Loop Dynamics Across Protein Tyrosine Phosphatase Subfamilies.

Protein Tyrosine Phosphatases (PTPs) regulate cellular signaling by balancing phosphotyrosine levels through a conserved WPD-loop that switches betwee...

Aug 28 2026 42665911
Enhanced diabetic retinopathy detection via multimodal fusion of fundus imaging features and clinical demographic information using verifiable convolutional neural network.

Traditional systems of ocular disease diagnosis and many deep learning-based systems are limited in their practice to analyzing fundus images from a s...

Aug 27 2026 42659913
Machine learning prediction models for diabetic kidney disease: A systematic review and meta-analysis.

BACKGROUND: Machine learning (ML) has emerged as a promising tool for predicting diabetic kidney disease (DKD), yet the performance and clinical utili...

Aug 27 2026 42660337
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