Latest AI and machine learning research in allergy & immunology for healthcare professionals.
BACKGROUND: Severe COVID-19 is a global health concern despite continuous vaccination campaigns because current therapies, such as dexamethasone and remdesivir, do not considerably improve immune function, especially in high-risk individuals. SARS-CoV-2-specific T cells (CoV-2-STs) from vaccinated or convalescent donors are a promising new treatment that can enhance clinical outcomes and viral-spe...
BACKGROUND: Mild bleeding disorders are the most common inherited bleeding disorders, often leading to perioperative haemorrhages. Preoperative screening for mild bleeding disorders remains challenging due to the limitations of existing screening tools, resulting in a substantial proportion of patients being referred for preoperative investigations. The aim of this study was to develop, externally...
Atopic dermatitis (AD) is the most common inflammatory skin disease and carries the highest disability-adjusted life-years burden, ranking 15th among ...
Artificial intelligence (AI) in environmental health science is revolutionizing data analysis and problem-solving approaches. These technologies facil...
The landscape of asthma management is undergoing significant transformation. This change is driven by several factors: deeper understanding of asthma ...
BACKGROUND: SERPING1, which encodes the C1 inhibitor (C1-INH) of the complement system, and plays a key regulator in regulating inflammatory responses...
Patients with chronic cough need to undergo a wide range of tests and rely on empirical medication to determine the underlying cause. Corticosteroid-r...
BACKGROUND: Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape of advanced non-small cell lung cancer (NSCLC). However, a su...
The heterogeneity and immunosuppressive characteristics of the tumor microenvironment present significant challenges to traditional treatment strategi...
The tumor microenvironment (TME) is composed of diverse heterogeneous components and plays a crucial role in immune cell infiltration, immune evasion,...
BACKGROUND: Cough sounds are accessible, non-invasive biomarkers for respiratory disease assessment and can be captured using consumer-grade smartphon...
T-cell bispecific antibodies (TCBs), a specialized subclass of bispecific antibodies (BsAbs), are engineered to simultaneously engage T cells and tumo...
Ferroptosis, an iron-dependent regulated cell death driven by lipid peroxidation, has emerged as a potential target in cancers resistant to apoptosis ...
PURPOSE OF REVIEW: Asthma continues to pose a serious global health issue affecting billions of people and causing significant morbidity. It is immuno...
Gene-by-gene differential expression analysis is a widely used supervised approach for interpreting single-cell RNA-sequencing (scRNA-seq) data. Howev...
Recurrent acute care visits are a common yet preventable outcome for many children with asthma. Machine learning (ML) applied to electronic medical re...
BACKGROUND: Microbial pathogens deploy sophisticated mechanisms to evade host immune responses, complicating the development of effective therapeutics...
OBJECTIVE: Pancreatic cancer (PC) poses a significant threat to patient quality of life. Ferroptosis, a novel form of non-apoptotic cell death, is imp...
Sepsis is a life-threatening organ malfunction induced by the host's abnormal reaction to infection. Sepsis can induce cellular senescence, thereby ex...